{"id":16977,"date":"2022-01-05T19:34:45","date_gmt":"2022-01-05T16:34:45","guid":{"rendered":"https:\/\/zdmaa.com\/understand-limits-of-genetic-tests-how-they-help\/"},"modified":"2022-01-06T00:07:29","modified_gmt":"2022-01-05T21:07:29","slug":"understand-limits-of-genetic-tests-how-they-help","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/ja\/understand-limits-of-genetic-tests-how-they-help\/","title":{"rendered":"\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9650\u754c\u3068\u305d\u308c\u304c\u3069\u306e\u3088\u3046\u306b\u5f79\u7acb\u3064\u304b\u3092\u7406\u89e3\u3059\u308b"},"content":{"rendered":"

\u907a\u4f1d\u5b50\u691c\u67fb\u306e\u9650\u754c\u3068\u305d\u308c\u304c\u3069\u306e\u3088\u3046\u306b\u5f79\u7acb\u3064\u304b\u3092\u7406\u89e3\u3059\u308b<\/span><\/span><\/span><\/span><\/p>\n

\n

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\u3057\u304b\u3057\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u6709\u7528\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u304c\u3093\u30ea\u30b9\u30af\u306e\u6e2c\u5b9a\u306b\u306f\u9650\u754c\u304c\u3042\u308b\u3053\u3068\u3092\u7406\u89e3\u3059\u308b\u3053\u3068\u304c\u91cd\u8981\u3067\u3059\u3002<\/span>\u305f\u3068\u3048\u3070\u3001\u5f7c\u3089\u306f\u3042\u306a\u305f\u304c\u764c\u3092\u767a\u75c7\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u78ba\u5b9f\u306b\u4e88\u6e2c\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u305a\u3001\u3042\u306a\u305f\u304c\u3069\u306e\u764c\u3092\u767a\u75c7\u3059\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u304b\u3092\u5224\u65ad\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u307e\u305b\u3093\u3002<\/span>\u907a\u4f1d\u5b50\u5909\u7570\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u306f\u3001\u304c\u3093\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u3044\u3053\u3068\u3092\u610f\u5473\u3059\u308b\u3060\u3051\u3067\u3042\u308a\u3001\u30ea\u30b9\u30af\u306b\u306f\u3044\u304f\u3064\u304b\u306e\u7a2e\u985e\u306e\u304c\u3093\u304c\u542b\u307e\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span>\u3059\u3079\u3066\u306e\u304c\u3093\u304c\u907a\u4f1d\u5b50\u5909\u7570\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/span>\u5b9f\u969b\u3001\u56fd\u7acb\u304c\u3093\u7814\u7a76\u6240\u306b\u3088\u308b\u3068\u3001\u907a\u4f1d\u6027\u306e\u907a\u4f1d\u7684\u6b20\u9665\u306f\u3001\u3059\u3079\u3066\u306e\u304c\u3093\u306e5\u301c10\u30d1\u30fc\u30bb\u30f3\u30c8\u306b\u3057\u304b\u95a2\u9023\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/span><\/span><\/p>\n

\u305f\u3060\u3057\u3001\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u3001\u4e73\u304c\u3093\u3001\u7d50\u8178\u76f4\u8178\u304c\u3093\u3001\u81b5\u81d3\u304c\u3093\u3001\u5375\u5de3\u304c\u3093\u3001\u524d\u7acb\u817a\u304c\u3093\u3001\u7532\u72b6\u817a\u304c\u3093\u3001\u5b50\u5bae\u304c\u3093\u306a\u3069\u3001\u4e00\u822c\u7684\u3067\u4e3b\u8981\u306a\u304c\u3093\u306e\u30ea\u30b9\u30af\u3092\u6e2c\u5b9a\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/span>\u691c\u67fb\u306f\u901a\u5e38\u3001\u4e16\u4ee3\u304b\u3089\u4e16\u4ee3\u3078\u3068\u53d7\u3051\u7d99\u304c\u308c\u308b\u6b20\u9665\u907a\u4f1d\u5b50\u3092\u7279\u5fb4\u3068\u3059\u308b\u907a\u4f1d\u6027\u304c\u3093\u75c7\u5019\u7fa4\u3092\u7279\u5b9a\u3057\u307e\u3059\u3002<\/span><\/span><\/p>\n

\u4e00\u822c\u7684\u306a\u75c7\u5019\u7fa4<\/span><\/span><\/h2>\n

\u3088\u308a\u4e00\u822c\u7684\u306a\u75c7\u5019\u7fa4\u306e\u3044\u304f\u3064\u304b\u306f\u6b21\u306e\u3068\u304a\u308a\u3067\u3059\u3002<\/span><\/span><\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\u75c7\u5019\u7fa4<\/span><\/span><\/th>\n\u907a\u4f1d\u5b50<\/span><\/span><\/th>\n\u95a2\u9023\u3059\u308b\u764c<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
\u907a\u4f1d\u6027\u4e73\u304c\u3093\u304a\u3088\u3073\u5375\u5de3\u304c\u3093\u75c7\u5019\u7fa4<\/span><\/span><\/td>\nBRCA1\u00d7BRCA2<\/span><\/span><\/span><\/span><\/td>\n\u4e73\u623f\u3001\u5375\u5de3\u3001\u524d\u7acb\u817a\u3001\u81b5\u81d3<\/span><\/span><\/td>\n<\/tr>\n
Li-Fraumeni\u75c7\u5019\u7fa4<\/span><\/span><\/td>\nTP53<\/span><\/span><\/td>\n\u4e73\u623f\u3001\u8edf\u90e8\u7d44\u7e54\u304a\u3088\u3073\u9aa8\u8089\u816b\u3001\u767d\u8840\u75c5\u3001\u8133\u304a\u3088\u3073\u526f\u814e\u76ae\u8cea\u764c<\/span><\/span><\/td>\n<\/tr>\n
\u30ab\u30a6\u30c7\u30f3\u75c7\u5019\u7fa4<\/span><\/span><\/td>\nPTEN<\/span><\/span><\/span><\/span><\/td>\n\u4e73\u623f\u3001\u7532\u72b6\u817a\u3001\u5b50\u5bae\u5185\u819c<\/span><\/span><\/td>\n<\/tr>\n
\u30ea\u30f3\u30c1\u75c7\u5019\u7fa4<\/span><\/span><\/td>\nMSH2\u00d7MLH1\u00d7MSH6\u00d7PMS2\u00d7EPCAM<\/span><\/span><\/span><\/span><\/td>\n\u8178\u3001\u5b50\u5bae\u5185\u819c\u3001\u5375\u5de3\u3001\u814e\u76c2\u3001\u81b5\u81d3\u3001\u809d\u81d3\u3001\u80c3\u3001\u8133\u3001\u4e73\u623f<\/span><\/span><\/td>\n<\/tr>\n
\u5bb6\u65cf\u6027\u5927\u8178\u817a\u816b\u75c7<\/span><\/span><\/td>\nAPC<\/span><\/span><\/span><\/span><\/td>\n\u8178\u3001\u8133\u3001\u80c3\u3001\u9aa8\u3001\u76ae\u819a\u306e\u60aa\u6027\u304a\u3088\u3073\u826f\u6027\u816b\u760d<\/span><\/span><\/td>\n<\/tr>\n
\u7db2\u819c\u82bd\u7d30\u80de\u816b<\/span><\/span><\/td>\nRB1<\/span><\/span><\/span><\/span><\/td>\n\u76ee\uff08\u7db2\u819c\uff09\u3001\u9ed2\u8272\u816b\u3001\u8edf\u90e8\u8089\u816b<\/span><\/span><\/td>\n<\/tr>\n
\u591a\u767a\u6027\u5185\u5206\u6ccc\u817a\u816b\u75c72\u578b<\/span><\/span><\/td>\n\u5f15\u9000\u3057\u305f\u0648<\/span><\/span><\/td>\n\u7532\u72b6\u817a\uff08\u5ef6\u9ac4\uff09\u3001\u526f\u814e\u306e\u826f\u6027\u816b\u760d<\/span><\/span><\/td>\n<\/tr>\n
\u30d5\u30a9\u30f3\u30d2\u30c3\u30da\u30eb\u30ea\u30f3\u30c0\u30a6\u75c7\u5019\u7fa4<\/span><\/span><\/td>\nVHL<\/span><\/span><\/span><\/span><\/td>\n\u814e\u81d3\u3001\u8907\u6570\u306e\u975e\u764c\u6027\u816b\u760d<\/span><\/span><\/td>\n<\/tr>\n
\u51fa\u5178\uff1a\u56fd\u7acb\u304c\u3093\u7814\u7a76\u6240<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u907a\u4f1d\u5b50\u691c\u67fb\u306f\u4e07\u4eba\u5411\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/span>\u300c\u8ab0\u304c\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u53d7\u3051\u308b\u3079\u304d\u304b\u306b\u3064\u3044\u3066\u3001\u3044\u304f\u3064\u304b\u306e\u5371\u967a\u4fe1\u53f7\u304c\u3042\u308a\u307e\u3059\u300d\u3068\u30b3\u30eb\u30d7\u30de\u30f3\u306f\u8a00\u3044\u307e\u3059\u3002<\/span>\u6b21\u306e\u5834\u5408\u306b\u3082\u907a\u4f1d\u5b50\u691c\u67fb\u3092\u691c\u8a0e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/span><\/span><\/p>\n

    \n
  • \u3042\u306a\u305f\u306f\u82e5\u3044\u3068\u304d\u306b\u3001\u307e\u305f\u306f\u4e73\u304c\u3093\u308450\u6b73\u672a\u6e80\u306e\u7d50\u8178\u304c\u3093\u306a\u3069\u306e\u7279\u5b9a\u306e\u304c\u3093\u306e\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u3088\u308a\u3082\u82e5\u3044\u3068\u304d\u306b\u304c\u3093\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/span><\/li>\n
  • \u304c\u3093\u306f\u3001\u4e73\u623f\u3084\u814e\u81d3\u306a\u3069\u30012\u3064\u306e\u30b0\u30eb\u30fc\u30d7\u306e\u4e21\u65b9\u306e\u81d3\u5668\u306b\u898b\u3089\u308c\u307e\u3059\uff08\u4e00\u822c\u306b\u4e21\u5074\u304c\u3093\u3068\u3057\u3066\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\uff09\u3002<\/span><\/span><\/li>\n
  • \u540c\u3058\u7a2e\u985e\u306e\u304c\u3093\u3068\u8a3a\u65ad\u3055\u308c\u305f\u5bb6\u65cf\u306e\u7247\u5074\u306b\u8907\u6570\u306e\u89aa\u621a\u304c\u3044\u308b\u306a\u3069\u3001\u304c\u3093\u306e\u5f37\u3044\u5bb6\u65cf\u6b74\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/span><\/li>\n
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  • \u5bb6\u65cf\u306f\u5e7c\u3044\u9803\u306b\u764c\u3068\u8a3a\u65ad\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/span><\/li>\n
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