{"id":20492,"date":"2022-01-10T02:44:59","date_gmt":"2022-01-09T23:44:59","guid":{"rendered":"https:\/\/zdmaa.com\/metastatic-breast-cancer-drugs-may-delay-chemotherapy\/"},"modified":"2022-01-10T14:53:19","modified_gmt":"2022-01-10T11:53:19","slug":"metastatic-breast-cancer-drugs-may-delay-chemotherapy","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/ja\/metastatic-breast-cancer-drugs-may-delay-chemotherapy\/","title":{"rendered":"\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u6cbb\u7642\u85ac\u306f\u5316\u5b66\u7642\u6cd5\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059"},"content":{"rendered":"<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\"><span class=\"\" style=\"vertical-align: inherit;\">\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u6cbb\u7642\u85ac\u306f\u5316\u5b66\u7642\u6cd5\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059<\/span><\/span><\/span><\/span><\/p>\n<div>\n<p><span class=\"first-letter\"><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">F<\/span><\/span><\/span><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u307e\u305f\u306f\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u306e\u60a3\u8005\u306f\u3001\u304c\u3093\u304c\u4f53\u306e\u4ed6\u306e\u90e8\u5206\u306b\u5e83\u304c\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u77e5\u3063\u3066\u3044\u308b\u3068\u3001\u6050\u308d\u3057\u3044\u5316\u5b66\u7642\u6cd5\u30ec\u30b8\u30e1\u30f3\u3068\u305d\u306e\u56f0\u96e3\u306a\u526f\u4f5c\u7528\u3092\u610f\u5473\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">\u305f\u3060\u3057\u3001\u30db\u30eb\u30e2\u30f3\u53d7\u5bb9\u4f53\u967d\u6027\u306e\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u3068HER2\u9670\u6027\u306e\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u306e\u60a3\u8005\u3055\u3093\u306e\u4e2d\u306b\u306f\u3001\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3092\u53d7\u3051\u305f\u5834\u5408\u3001\u4e73\u304c\u3093\u306e\u5316\u5b66\u7642\u6cd5\u3092\u6700\u59271\u5e74\u9045\u3089\u305b\u308b\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/span><span style=\"vertical-align: 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Ethal\u3001MD\u3001\u8840\u6db2\u5c02\u9580\u533b\u304a\u3088\u3073\u816b\u760d\u5b66\u8005\u3001\u816b\u760d\u5185\u79d1<\/span><\/span><\/em><\/p><\/blockquote>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u30ad\u30ca\u30fc\u30bc\u963b\u5bb3\u5264\u3068\u306f\u4f55\u3067\u3059\u304b\uff1f<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u3053\u308c\u3089\u306e\u65b0\u3057\u3044\u85ac\u306f\u3001\u30ad\u30ca\u30fc\u30bc\u963b\u5bb3\u5264\u3068\u547c\u3070\u308c\u308b\u6a19\u7684\u7642\u6cd5\u306e\u305f\u3081\u306e\u6297\u304c\u3093\u5264\u306e\u4e00\u822c\u7684\u306a\u30af\u30e9\u30b9\u306b\u5c5e\u3057\u3066\u3044\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">\u30ad\u30ca\u30fc\u30bc\u306f\u7d30\u80de\u5185\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308a\u3001\u9001\u4fe1\u6a5f\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001\u4ed6\u306e\u7d30\u80de\u304b\u3089\u4fe1\u53f7\u3092\u53d7\u4fe1\u3057\u3066\u200b\u200b\u304b\u3089\u3001\u7d30\u80de\u306e\u6838\u306b\u6307\u793a\u3092\u9001\u4fe1\u3057\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">\u4fe1\u53f7\u304c\u9001\u4fe1\u3055\u308c\u308b\u3068\u3001\u30bb\u30eb\u306f\u6210\u9577\u3001\u5206\u88c2\u3001\u3055\u3089\u306b\u306f\u9589\u9396\u306a\u3069\u3001\u4efb\u610f\u306e\u6570\u306e\u6a5f\u80fd\u3092\u5b9f\u884c\u3067\u304d\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">\u3053\u308c\u3089\u306e\u4e73\u304c\u3093\u6cbb\u7642\u85ac\u306f\u3001\u7d30\u80de\u306e\u6210\u9577\u3068\u5206\u88c2\u306e\u8abf\u7bc0\u3092\u52a9\u3051\u308b2\u3064\u306e\u30d7\u30ed\u30c6\u30a4\u30f3\u30ad\u30ca\u30fc\u30bcCDK4\u3068CDK6\u3092\u6a19\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">\u3053\u308c\u3089\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u3068\u3001\u304c\u3093\u7d30\u80de\u306e\u6210\u9577\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">HR\u967d\u6027\u304a\u3088\u3073HER\u9670\u6027\u306e\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u306e\u4e00\u90e8\u306e\u60a3\u8005\u306f\u3001CDK4 \/ 6\u963b\u5bb3\u5264\u3068\u30db\u30eb\u30e2\u30f3\u7642\u6cd5\u3092\u4f75\u7528\u3057\u305f\u5834\u5408\u306b\u826f\u597d\u306a\u7d50\u679c\u3092\u7d4c\u9a13\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/span><\/p>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u30d5\u30a3\u30e9\u30c7\u30eb\u30d5\u30a3\u30a2\u306b\u3042\u308b\u5f53\u9662\u306e\u8840\u6db2\u5c02\u9580\u533b\u304a\u3088\u3073\u816b\u760d\u5b66\u8005\u3001\u533b\u7642\u816b\u760d\u5b66\u8005\u3001\u304a\u3088\u3073\u4e73\u304c\u3093\u30bb\u30f3\u30bf\u30fc\u306e\u6240\u9577\u3067\u3042\u308b\u30b5\u30e9\u30df\u30e9\u30fb\u30a2\u30a4\u30b5\u30eb\u533b\u5b66\u535a\u58eb\u306f\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">\u300c\u3057\u304b\u3057\u3001CDK 4\/6\u3092\u6a19\u7684\u3068\u3059\u308b\u3053\u306e\u4ed6\u306e\u6cbb\u7642\u6cd5\u3092\u8ffd\u52a0\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u30012\u5e74\u4ee5\u4e0a\u306b\u308f\u305f\u3063\u3066\u3088\u308a\u826f\u3044\u53cd\u5fdc\u304c\u5f97\u3089\u308c\u307e\u3057\u305f\u3002\u91cd\u8981\u306a\u3053\u3068\u306b\u3001\u8ee2\u79fb\u6027\u764c\u306e\u5316\u5b66\u7642\u6cd5\u3092\u53d7\u3051\u308b\u591a\u304f\u306e\u4eba\u3005\u306f\u3001\u7279\u306b\u809d\u81d3\u3084\u3053\u306e\u6cbb\u7642\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u3088\u308a\u3001\u5316\u5b66\u7642\u6cd5\u3092\u6700\u592727\u304b\u6708\u307e\u305f\u306f28\u304b\u6708\u5ef6\u671f\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3057\u305f\u3002\u305d\u308c\u306f\u5927\u304d\u306a\u9055\u3044\u3092\u3082\u305f\u3089\u3057\u307e\u3057\u305f\u3002\u300d<\/span><\/span><\/p>\n<h2><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">CDK 4\/6\u963b\u5bb3\u5264\uff1a<\/span><\/span><\/h2>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u73fe\u5728\u307e\u3067\u306b\u3001FDA\u306f\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u306e\u6cbb\u7642\u306e\u305f\u3081\u306b3\u3064\u306eCDK4 \/ 6\u963b\u5bb3\u5264\u3092\u627f\u8a8d\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/span><\/p>\n<ul>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Palbociclib\uff08Ibrance <\/span><\/span><sup><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u00ae<\/span><\/span><\/sup><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u30012015\u5e74\u306b\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\uff09\u3001<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Ribusiclaib\uff08Kescala <\/span><\/span><sup><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u00ae<\/span><\/span><\/sup><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\uff09\u30012017\u5e744\u6708\u306b\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f<\/span><\/span><\/li>\n<li><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u30a2\u30d9\u30de\u30b7\u30af\u30ea\u30d6\uff08Verzenio\u2122\uff09\u30012017\u5e749\u6708\u627f\u8a8d<\/span><\/span><\/li>\n<\/ul>\n<p><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">Palbociclib\u3068ribociclib\u306f\u901a\u5e38\u3001\u6297\u30a8\u30b9\u30c8\u30ed\u30b2\u30f3\u85ac\u30d5\u30eb\u30d9\u30b9\u30c8\u30e9\u30f3\u30c8\uff08\u30d5\u30a1\u30b9\u30ed\u30c7\u30c3\u30af\u30b9\u3068\u4e00\u7dd2\u306b\u4e0e\u3048\u3089\u308c\u3066\u3044\u308b<\/span><\/span><sup><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u00ae<\/span><\/span><\/sup><span style=\"vertical-align: inherit;\"><span style=\"vertical-align: inherit;\">\u306e\u30db\u30eb\u30e2\u30f3\u3092\u8abf\u7bc0\u3057\u307e\u3059\uff09\u3002<\/span><span style=\"vertical-align: inherit;\">\u30a2\u30d9\u30de\u30b7\u30af\u30ea\u30d6\u306f\u3001\u5358\u72ec\u7642\u6cd5\u3068\u3057\u3066\u627f\u8a8d\u3055\u308c\u305f\u6700\u521d\u306eCDK4 \/ 6\u963b\u5bb3\u5264\u3067\u3059\u3002<\/span><span style=\"vertical-align: inherit;\">CDK 4\/6\u963b\u5bb3\u5264\u306f\u3001HER\u967d\u6027\u304a\u3088\u3073HER\u9670\u6027\u306e\u4e73\u304c\u3093\u3067\u306e\u307f\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u80ba\u304c\u3093\u3001\u524d\u7acb\u817a\u304c\u3093\u3001\u305d\u306e\u4ed6\u306e\u7a2e\u985e\u306e\u4e73\u304c\u3093\u306a\u3069\u3001\u4ed6\u306e\u304c\u3093\u306e\u6cbb\u7642\u306b\u4f7f\u7528\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3092\u5224\u65ad\u3059\u308b\u305f\u3081\u306e\u81e8\u5e8a\u8a66\u9a13\u304c\u9032\u884c\u4e2d\u3067\u3059\u3002<\/span><span style=\"vertical-align: 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F\u307e\u305f\u306f\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u306e\u60a3\u8005\u306f\u3001\u304c\u3093\u304c\u4f53\u306e\u4ed6\u306e\u90e8\u5206\u306b\u5e83\u304c &hellip;<\/p>\n","protected":false},"author":1,"featured_media":20421,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[],"class_list":["post-20492","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-20"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u8ee2\u79fb\u6027\u4e73\u304c\u3093\u6cbb\u7642\u85ac\u306f\u5316\u5b66\u7642\u6cd5\u3092\u9045\u3089\u305b\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059 - zdmaa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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