{"id":23966,"date":"2022-01-12T20:14:47","date_gmt":"2022-01-12T17:14:47","guid":{"rendered":"https:\/\/zdmaa.com\/five-things-you-should-know-about-car-t-cell-therapy\/"},"modified":"2022-01-12T23:31:44","modified_gmt":"2022-01-12T20:31:44","slug":"five-things-you-should-know-about-car-t-cell-therapy","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/ja\/five-things-you-should-know-about-car-t-cell-therapy\/","title":{"rendered":"CAR-T\u7d30\u80de\u7642\u6cd5\u306b\u3064\u3044\u3066\u77e5\u3063\u3066\u304a\u304f\u3079\u304d5\u3064\u306e\u3053\u3068"},"content":{"rendered":"

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\n

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\u300cCAR-T\u7d30\u80de\u7642\u6cd5\u306e\u53ef\u80fd\u6027\u306b\u975e\u5e38\u306b\u8208\u596e\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u5c06\u6765\u591a\u304f\u306e\u764c\u3092\u6cbb\u7642\u3059\u308b\u65b9\u6cd5\u306b\u304a\u3051\u308b\u91cd\u8981\u306a\u30de\u30a4\u30eb\u30b9\u30c8\u30fc\u30f3\u3067\u3059\u3002\u300d<\/span><\/span>\u2014\u30aa\u30f3\u30b3\u30ed\u30b8\u30b9\u30c8\u304a\u3088\u3073\u8840\u6db2\u5c02\u9580\u533b\u306eAlan Tan<\/span><\/span><\/em><\/p><\/blockquote>\n

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    \n
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    CAR T\u7d30\u80de\u7642\u6cd5\u306f\u767d\u8840\u75c5\u306b\u5bfe\u3057\u3066\u306e\u307f\u627f\u8a8d\u3055\u308c\u3066\u304a\u308a\u3001\u56fa\u5f62\u816b\u760d\u306b\u304a\u3051\u308b\u305d\u306e\u6027\u80fd\u3092\u6e2c\u5b9a\u3059\u308b\u81e8\u5e8a\u8a66\u9a13\u306f\u5968\u52b1\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/span>CAR T\u7d30\u80de\u306f\u3001\u7279\u5b9a\u306e\u7a2e\u985e\u306eB\u7d30\u80de\uff08\u611f\u67d3\u3068\u6226\u3046\u6297\u4f53\u3092\u4f5c\u308b\u767d\u8840\u7403\uff09\u3092\u6a19\u7684\u306b\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u767d\u8840\u75c5\u3092\u6cbb\u7642\u3057\u307e\u3059\u3002<\/span>\u3057\u304b\u3057\u3001\u591a\u304f\u306e\u56fa\u5f62\u816b\u760d\u306b\u306f\u8907\u6570\u306e\u907a\u4f1d\u5b50\u5909\u7570\u304c\u3042\u308a\u3001\u85ac\u5264\u304c\u514d\u75ab\u5fdc\u7b54\u3092\u8a98\u767a\u3059\u308b\u305f\u3081\u306b\u6a19\u7684\u306b\u3057\u3088\u3046\u3068\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u816b\u760d\u306e\u6210\u9577\u3092\u4fc3\u9032\u3059\u308b\u5358\u4e00\u306e\u6a19\u7684\u3092\u7279\u5b9a\u3059\u308b\u3053\u3068\u306f\u56f0\u96e3\u3067\u3059\u3002<\/span>\u3055\u3089\u306b\u3001\u4e00\u90e8\u306e\u56fa\u5f62\u816b\u760d\u306f\u514d\u75ab\u7d30\u80de\u3092\u52d5\u54e1\u3057\u3066\u7834\u58ca\u7684\u306a\u884c\u52d5\u3092\u8d77\u3053\u3057\u3001\u816b\u760d\u306e\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u8010\u6027\u3092\u9ad8\u3081\u307e\u3059\u3002<\/span>\u300c\u56fa\u5f62\u816b\u760d\u306e\u96e3\u3057\u3055\u306f\u3001\u305d\u308c\u304c\u4f55\u3092\u6a19\u7684\u3068\u3057\u3001\u305d\u306e\u6a19\u7684\u304cT\u7d30\u80de\u306b\u3069\u306e\u3088\u3046\u306b\u30d7\u30ed\u30b0\u30e9\u30e0\u3055\u308c\u3066\u3044\u308b\u304b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u300d<\/span>\u30bf\u30f3\u535a\u58eb\u3001\u300c\u305d\u308c\u306f\u3057\u3070\u3089\u304f\u6642\u9593\u304c\u304b\u304b\u308b\u3067\u3057\u3087\u3046\u3002\u300d<\/span><\/span><\/p>\n

    CAR T\u7d30\u80de\u7642\u6cd5\u306f\u3001\u6df1\u523b\u306a\u526f\u4f5c\u7528\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span><\/span><\/h2>\n

    CAR T\u7d30\u80de\u7642\u6cd5\u306e\u526f\u4f5c\u7528\u3001\u7279\u306b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u653e\u51fa\u75c7\u5019\u7fa4\uff08CRS\uff09\u3068\u3057\u3066\u77e5\u3089\u308c\u308b\u72b6\u614b\u306f\u3001\u751f\u547d\u3092\u8105\u304b\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002<\/span>\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306f\u3001\u514d\u75ab\u7cfb\u306e\u8abf\u7bc0\u3092\u52a9\u3051\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002<\/span>\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u3001CAR T\u7d30\u80de\u7642\u6cd5\u306e\u60a3\u8005\u306f\u3001\u5065\u5eb7\u306a\u7d30\u80de\u3084\u7d44\u7e54\u3092\u653b\u6483\u3057\u59cb\u3081\u308b\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\u306b\u5727\u5012\u3055\u308c\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u69d8\u306e\u75c7\u72b6\u3001\u9ad8\u71b1\u3001\u751f\u547d\u3092\u8105\u304b\u3059\u795e\u7d4c\u5b66\u7684\u526f\u4f5c\u7528\u3001\u304a\u3088\u3073\u305d\u306e\u4ed6\u306e\u6df1\u523b\u306a\u72b6\u614b\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002<\/span>\u7c73\u56fd\u98df\u54c1\u533b\u85ac\u54c1\u5c40\uff08FDA\uff09\u306f\u3001CAR T\u7d30\u80de\u7642\u6cd5\u3092\u4f7f\u7528\u3057\u3066\u3044\u308b\u75c5\u9662\u306b\u3001CRS\u3092\u8a8d\u8b58\u304a\u3088\u3073\u7ba1\u7406\u3059\u308b\u305f\u3081\u306e\u8a8d\u5b9a\u304a\u3088\u3073\u30c8\u30ec\u30fc\u30cb\u30f3\u30b0\u3092\u53d7\u3051\u305f\u30b9\u30bf\u30c3\u30d5\u3092\u914d\u7f6e\u3059\u308b\u3053\u3068\u3092\u7fa9\u52d9\u4ed8\u3051\u3066\u3044\u307e\u3059\u3002<\/span>CAR T\u7d30\u80de\u306f\u5065\u5eb7\u306aB\u7d30\u80de\u3082\u653b\u6483\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u4e00\u90e8\u306e\u60a3\u8005\u3067\u306f\u611f\u67d3\u306e\u30ea\u30b9\u30af\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002<\/span><\/span><\/p>\n

    \u5b8c\u5168\u306a\u6cbb\u7642\u3092\u5b8c\u4e86\u3059\u308b\u306b\u306f\u6570\u9031\u9593\u304b\u304b\u308a\u307e\u3059\u3002<\/span><\/span><\/h2>\n

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    CAR T\u7d30\u80de\u306f\u3001\u6c38\u4e45\u306b\u6a5f\u80fd\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/span><\/h2>\n

    T\u7d30\u80de\u304c\u6709\u5bb3\u306a\u7d30\u80de\u3084\u30a6\u30a4\u30eb\u30b9\u3092\u653b\u6483\u3059\u308b\u3068\u3001\u518d\u3073\u653b\u6483\u3057\u305f\u5834\u5408\u306b\u305d\u308c\u3089\u3092\u8a18\u61b6\u3059\u308b\u3088\u3046\u306b\u30d7\u30ed\u30b0\u30e9\u30e0\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span>CAR T\u7d30\u80de\u3082\u4f8b\u5916\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30d7\u30ed\u30bb\u30b9\u304c\u9069\u5207\u306b\u6a5f\u80fd\u3057\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u60a3\u8005\u306e\u6b8b\u308a\u306e\u751f\u6daf\u306b\u308f\u305f\u3063\u306624\u6642\u9593\u5e74\u4e2d\u7121\u4f11\u3067\u52e4\u52d9\u3057\u3066\u3044\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/span>\u7406\u8ad6\u7684\u306b\u306f\u3001\u764c\u7d30\u80de\u304c\u518d\u3073\u73fe\u308c\u308b\u3068\u3001\u60a3\u8005\u306e\u77e5\u3089\u306a\u3044\u3046\u3061\u306b\u3001CART\u7d30\u80de\u304c\u305d\u308c\u3089\u3092\u8a8d\u8b58\u3057\u3066\u6bba\u3057\u307e\u3059\u3002<\/span>\u30bf\u30f3\u535a\u58eb\u306f\u3001\u300cCAR-T\u7d30\u80de\u306f\u30011\u56de\u306e\u6cbb\u7642\u3067\u9577\u671f\u7684\u306a\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u822c\u7684\u306b\u3001\u4fee\u98fe\u3055\u308c\u305fT\u7d30\u80de\u304c\u6ce8\u5165\u3055\u308c\u308b\u3068\u3001\u4f53\u5185\u306b\u6b8b\u308a\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u300c\u751f\u85ac\u300d\u3092\u6295\u4e0e\u3059\u308b\u306e\u3068\u4f3c\u3066\u3044\u307e\u3059\u3002\u3042\u306a\u305f\u306e\u4eba\u751f\u306e\u6b8b\u308a\u306e\u305f\u3081\u306b\u3042\u306a\u305f\u306e\u4f53\u3002\u300d<\/span><\/span><\/span><\/span><\/p>\n

    \u767d\u8840\u75c5\u3068\u975e\u30db\u30b8\u30ad\u30f3\u30ea\u30f3\u30d1\u816b\u306e\u8a73\u7d30<\/span><\/span><\/span><\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

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