{"id":21263,"date":"2022-01-09T23:37:51","date_gmt":"2022-01-09T20:37:51","guid":{"rendered":"https:\/\/zdmaa.com\/what-are-regional-cancer-therapies-how-do-they-help\/"},"modified":"2022-01-11T00:54:59","modified_gmt":"2022-01-10T21:54:59","slug":"what-are-regional-cancer-therapies-how-do-they-help","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/tr\/what-are-regional-cancer-therapies-how-do-they-help\/","title":{"rendered":"B\u00f6lgesel kanser tedavileri nelerdir ve nas\u0131l yard\u0131mc\u0131 olurlar?"},"content":{"rendered":"

B\u00f6lgesel kanser tedavileri nelerdir ve nas\u0131l yard\u0131mc\u0131 olurlar?<\/span><\/span><\/span><\/span><\/p>\n

\n

\u0130leri kanser, \u00f6zellikle karaci\u011fer ve akci\u011ferler gibi v\u00fccudun hayatta kalmas\u0131 i\u00e7in gerekli olan hayati organlara yay\u0131ld\u0131\u011f\u0131nda tedavi edilmesi zor olabilir. <\/span>Zorluk sadece t\u00fcm\u00f6re ula\u015fmak de\u011fil, etkilenen hayati organlara zarar vermeden ve hastan\u0131n sa\u011fl\u0131\u011f\u0131na daha fazla zarar vermeden tedavi etmektir. <\/span>Ancak daha hedefe y\u00f6nelik bir tedavi yakla\u015f\u0131m\u0131, bu hastalara potansiyel bir se\u00e7enek sunarak, doktorlar\u0131n v\u00fccudun geri kalan\u0131n\u0131 zararl\u0131 toksisite seviyelerine maruz b\u0131rakmadan do\u011frudan t\u00fcm\u00f6re y\u00fcksek dozda kemoterapi veya radyasyon vermelerine olanak tan\u0131r. <\/span>Organa y\u00f6nelik terapiler veya b\u00f6lgesel terapiler olarak adland\u0131r\u0131lan tedaviler, bunlar\u0131 t\u00fcm v\u00fccuda vermek yerine belirli bir hedef se\u00e7me stratejisidir. <\/span>Tulsa’daki hastanemizde cerrahi onkolog ve karaci\u011fer ve pankreas biliyer cerrah\u0131 olan Pragateshwar Thironavukarasu, “Bir hastan\u0131n hastal\u0131\u011f\u0131n\u0131, kanserin v\u00fccutta en k\u00f6t\u00fc etkiye sahip olabilece\u011fi yeri ele alacak \u015fekilde y\u00f6netmek i\u00e7in \u00e7al\u0131\u015f\u0131yoruz” diyor.<\/span><\/span><\/p>\n

B\u00f6lgesel tedaviler ilk olarak 1950’lerde, cerrahlar\u0131n ameliyat\u0131n \u00e7ok invaziv oldu\u011fu veya hastalar i\u00e7in potansiyel olarak zararl\u0131 oldu\u011fu veya kanserin cerrahi olarak \u00e7\u0131kar\u0131lamad\u0131\u011f\u0131 durumlarda daha g\u00fcvenli bir alternatife olan ihtiyac\u0131 fark etmesinden sonra ortaya \u00e7\u0131kt\u0131. <\/span>Phoenix yak\u0131nlar\u0131ndaki hastanemizde cerrahi onkolog olan Diego Muilenburg, \u201cTedavinin amac\u0131 t\u00fcm kanserleri \u00e7\u0131karmak oldu\u011funda ve kanser i\u00e7in ameliyat yap\u0131labildi\u011finde karaci\u011fer cerrahisi hala standart tedavi olarak kabul edilir\u201d diyor. <\/span>“Herhangi bir nedenle cerrahi bir se\u00e7enek olmad\u0131\u011f\u0131nda b\u00f6lgesel tedaviler iyi bir se\u00e7enektir.”<\/span><\/span><\/p>\n

Dr. Muilenburg, genellikle karaci\u011feri hedef alan tedaviler olarak adland\u0131r\u0131lan b\u00f6lgesel karaci\u011fer tedavileri durumunda “organlar\u0131n korunmas\u0131yla ilgilidir” diyor. <\/span>“T\u00fcm\u00f6r\u00fc \u00f6ld\u00fcrmeye devam ederken m\u00fcmk\u00fcn oldu\u011funca sa\u011fl\u0131kl\u0131 karaci\u011feri kurtarmaya \u00e7al\u0131\u015f\u0131yoruz.” <\/span>Dr. Muilenburg, karaci\u011ferin b\u00f6lgesel tedaviler i\u00e7in pop\u00fcler bir hedef oldu\u011funu \u00e7\u00fcnk\u00fc metastatik hastal\u0131\u011f\u0131n en yayg\u0131n b\u00f6lgelerinden biri oldu\u011funu, kendi kendine yenilenme kabiliyetine sahip oldu\u011funu ve “darbeyi kald\u0131rabilece\u011fini” s\u00f6yl\u00fcyor. organ genellikle yoktur. <\/span>Radyasyonun di\u011fer organlara verdi\u011fi zarar\u0131 vermez.<\/span><\/span><\/p>\n

Karaci\u011feri hedef alan tedaviler<\/span><\/span><\/h2>\n

Karaci\u011feri hedef alan tedaviler \u00e7e\u015fitli \u015fekillerde sunulmaktad\u0131r. <\/span>En yayg\u0131n olanlar\u0131:<\/span><\/span><\/p>\n

    \n
  • Hepatik arter pompas\u0131:<\/span><\/span><\/strong> Cerrah, karaci\u011fere kan sa\u011flayan ana kan damar\u0131 olan hepatik artere bir t\u00fcp yerle\u015ftirir ve onu s\u00fcrekli olarak do\u011frudan karaci\u011fere kemoterapi veren k\u00fc\u00e7\u00fck implante edilmi\u015f bir pompaya ba\u011flar.<\/span><\/span><\/li>\n
  • Hepatik kimyasal emboli ve radyasyon embolisi:<\/span><\/span><\/strong> Kas\u0131k i\u00e7ine yerle\u015ftirilen minimal invaziv bir kateter arac\u0131l\u0131\u011f\u0131yla, karaci\u011fer arterlerine k\u00fc\u00e7\u00fck partik\u00fcller enjekte edilir, bu da t\u00fcm\u00f6re giden kan ak\u0131\u015f\u0131n\u0131 bloke eder, b\u00fcy\u00fcme i\u00e7in ihtiya\u00e7 duydu\u011fu oksijen ve besin kayna\u011f\u0131n\u0131 bloke eder ve ayn\u0131 anda y\u00fcksek doz sa\u011flar. – do\u011frudan t\u00fcm\u00f6r \u00fczerine kemoterapi veya radyasyon dozu.<\/span><\/span><\/li>\n
  • Radyofrekans hepatektomi ve mikrodalga rezeksiyonu: Onkolog<\/span><\/span><\/strong> , t\u00fcm\u00f6r\u00fc yakmak i\u00e7in radyofrekans veya mikrodalga g\u00fc\u00e7 kayna\u011f\u0131ndan gelen \u0131s\u0131y\u0131 kullan\u0131r.<\/span><\/span><\/li>\n<\/ul>\n

    B\u00f6lgesel tedaviler, kemoterapinin \u0131s\u0131t\u0131ld\u0131\u011f\u0131 hipertermi ad\u0131 verilen terap\u00f6tik bir y\u00f6nteme de izin verir. <\/span>T\u00fcm\u00f6r i\u00e7indeki artan s\u0131cakl\u0131k, kanser h\u00fccrelerinin y\u00fcksek s\u0131cakl\u0131klara tahamm\u00fcl edemeyen k\u0131s\u0131mlar\u0131n\u0131n yan\u0131 s\u0131ra sa\u011fl\u0131kl\u0131 h\u00fccrelere de zarar verecek \u015fekilde tasarlanm\u0131\u015ft\u0131r.<\/span><\/span><\/p>\n

    Dr. Thironavucarasu, baz\u0131 kanserleri tedavi etmek i\u00e7in kullan\u0131labilecek birka\u00e7 b\u00f6lgesel tedavi olabilir, ancak onkolo\u011funuzun her birini nas\u0131l uygulayaca\u011f\u0131n\u0131 ve hangi se\u00e7ene\u011fi ne zaman kullanaca\u011f\u0131n\u0131 bilmesi \u00f6nemlidir, diyor. <\/span>\u00d6rne\u011fin, radyasyon embolizasyonundan sonra karaci\u011fer t\u00fcm\u00f6r\u00fcn\u00fc tedavi etmek i\u00e7in bir karaci\u011fer pompas\u0131 kullan\u0131lamaz \u00e7\u00fcnk\u00fc pompan\u0131n kemoterapi vermek i\u00e7in kullanaca\u011f\u0131 kan damarlar\u0131 bloke edilir. <\/span>Dr. Thironavukarasu, “T\u00fcm ko\u015fullar\u0131 ayn\u0131 topikal tedaviyle tedavi etmek, kanseri tedavi etmek i\u00e7in benzersiz bir yakla\u015f\u0131md\u0131r, ancak kanser tek bedene uyan bir \u015fey de\u011fildir” diyor.<\/span><\/span><\/p>\n

    Kanser de durgun de\u011fildir. <\/span>Evrilir ve b\u00f6lgesel tedavileri de vard\u0131r. <\/span>Chicago yak\u0131nlar\u0131ndaki hastanemizde cerrahinin t\u0131bbi direkt\u00f6r\u00fc ve cerrahi onkolog olan Charles Komen Brown, sadece yirmi y\u0131l \u00f6nce, asl\u0131nda b\u00f6lgesel tedavilerin deneysel olarak kabul edildi\u011fini ve \u00e7o\u011fu cerrah\u0131n bunlar\u0131 kullanmad\u0131\u011f\u0131n\u0131 s\u00f6yl\u00fcyor. <\/span>\u201cO zamanlar nerede oldu\u011fumuzu, \u015fu anda bulundu\u011fumuz yerle kar\u015f\u0131la\u015ft\u0131r\u0131rsan\u0131z, bir\u00e7ok b\u00f6lgesel tedavinin baz\u0131 kanserler i\u00e7in standart olarak kabul edildi\u011fi yerlerde, b\u00f6lgesel tedavi uzun bir yol kat etti\u201d diyor.<\/span><\/span><\/p>\n

    B\u00f6lgesel Kanser Tedavileri<\/span><\/span><\/h2>\n

    Karaci\u011fere ek olarak, v\u00fccudun bu b\u00f6lgelerindeki t\u00fcm\u00f6rlere sald\u0131rmak i\u00e7in topikal tedaviler kullan\u0131l\u0131r:<\/span><\/span><\/p>\n

      \n
    • Kar\u0131n<\/span><\/span><\/strong> , periton y\u00fczeyinde yayg\u0131n bir malignite b\u00f6lgesidir. <\/span>Periton y\u00fczeyindeki maligniteler, kar\u0131n b\u00f6lgesini kaplayan ince, \u015feffaf zar olan peritonun astar\u0131n\u0131 i\u00e7erir. <\/span>Bazen apendiks, rektum, kolon, mide, yumurtal\u0131k veya di\u011fer organlardaki tespit edilemeyen t\u00fcm\u00f6rler bu y\u00fczeylere yay\u0131l\u0131r.<\/span><\/span><\/li>\n
    • Kolorektal kanser, melanom ve sarkom i\u00e7in yayg\u0131n metastaz b\u00f6lgeleri olan <\/span>akci\u011ferler<\/span><\/strong> . <\/span>Dr. Muilenburg, akci\u011ferlerin karaci\u011fer gibi baz\u0131 topikal tedavilerin hedefi olabilece\u011fini s\u00f6yl\u00fcyor.<\/span><\/span><\/li>\n
    • Deri kanserini tedavi etmek i\u00e7in topikal tedavilerin kullan\u0131labilece\u011fi <\/span>organlar<\/span><\/strong> . <\/span>\u0130zole uzuv enjeksiyonlar\u0131nda, v\u00fccudun geri kalan\u0131na zarar vermemek i\u00e7in bacak veya kolu tedavi etmek i\u00e7in y\u00fcksek dozda s\u0131cak kemoterapi kullan\u0131labilir.<\/span><\/span><\/li>\n<\/ul>\n

      Kanser anlay\u0131\u015f\u0131m\u0131zdaki ve b\u00f6lgesel tedavilerin onu tedavi etme bi\u00e7imindeki de\u011fi\u015fiklikler, onkologlar\u0131n tedaviyi kullanma \u015feklini etkilemeye devam edecektir. <\/span>Gelecekte, Dr. Brown, kan dola\u015f\u0131m\u0131nda dola\u015fan ve v\u00fccuttaki h\u00fccreleri etkileyen kemoterapi ve imm\u00fcnoterapi ila\u00e7lar\u0131 gibi v\u00fccudun sistemlerini etkileyen kanser tedavilerinin, kanseri tedavi etmek i\u00e7in b\u00f6lgesel tedavilerle giderek daha fazla birle\u015ftirilece\u011fine inan\u0131yor. <\/span>“Karaci\u011fer kanserini tedavi ederken karaci\u011fer radyoembolizasyonunu sistemik kemoterapi ile birle\u015ftirerek ve bir t\u00fcr brakiterapi olan y\u00fcksek s\u0131cakl\u0131k intraperitoneal kemoterapiyi (HIPEC) t\u00fcm\u00f6r malignitesini tedavi etmek i\u00e7in sistemik kemoterapiyle birle\u015ftirerek zaten bunlar\u0131n bir k\u0131sm\u0131n\u0131 yap\u0131yoruz. peritonun y\u00fczeyini etkiler. <\/span>diyor. <\/span>Kahverengi. <\/span>“Bence gelece\u011fin oras\u0131 olacak.”<\/span><\/span><\/p>\n

      Tabii ki nihai hedef, topikal tedavileri tamamen ortadan kald\u0131rmak olabilir. <\/span>Dr. Muilenburg, “Uzun vadede, b\u00f6lgesel tedaviler yapmak zorunda kalmasayd\u0131k harika olurdu \u00e7\u00fcnk\u00fc sistemik tedaviler yeterince iyi \u00e7al\u0131\u015f\u0131yor ve art\u0131k onlara ihtiyac\u0131m\u0131z yok” diyor. <\/span>“\u015eu anda bir b\u00f6lgeyi tedavi ediyoruz \u00e7\u00fcnk\u00fc kanseri g\u00f6rd\u00fc\u011f\u00fcm\u00fcz tek yer oras\u0131. Ama baz\u0131 durumlarda kanser te\u015fhis ara\u00e7lar\u0131yla tespit edilemeyecek kadar mikroskobik miktarlarda zaten ba\u015fka b\u00f6lgelere yay\u0131lm\u0131\u015f durumda. Tedavi edebilsek daha iyi olur. v\u00fccut sistematik olarak ve t\u00fcm kanser h\u00fccrelerini hedef al\u0131yor.\u201d Bu lokalize alanlar\u0131 hedeflemek yerine metastaz yap\u0131yor, ancak \u015fimdilik bu tedaviler birka\u00e7 spesifik kanserle s\u0131n\u0131rl\u0131.\u201d<\/span><\/span><\/p>\n

      V\u00fccudun genellikle topikal tedavilerle tedavi edilen bir par\u00e7as\u0131 olan karaci\u011fer kanseri hakk\u0131nda daha fazla bilgi edinin.<\/span><\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

      B\u00f6lgesel kanser tedavileri nelerdir ve nas\u0131l yard\u0131mc\u0131 olurlar? \u0130leri kanser, \u00f6zellikle karaci\u011fer ve akci\u011ferler gibi v\u00fccudun hayatta kalmas\u0131 i\u00e7in gerekli olan hayati organlara yay\u0131ld\u0131\u011f\u0131nda tedavi edilmesi zor olabilir. Zorluk sadece t\u00fcm\u00f6re ula\u015fmak de\u011fil, etkilenen hayati organlara zarar vermeden ve hastan\u0131n sa\u011fl\u0131\u011f\u0131na daha fazla zarar vermeden tedavi etmektir. Ancak daha hedefe y\u00f6nelik bir tedavi yakla\u015f\u0131m\u0131, bu …<\/p>\n","protected":false},"author":1,"featured_media":20040,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-21263","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-tr"],"yoast_head":"\nB\u00f6lgesel kanser tedavileri nelerdir ve nas\u0131l yard\u0131mc\u0131 olurlar? - zdmaa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zdmaa.com\/tr\/what-are-regional-cancer-therapies-how-do-they-help\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"B\u00f6lgesel kanser tedavileri nelerdir ve nas\u0131l yard\u0131mc\u0131 olurlar? - zdmaa\" \/>\n<meta property=\"og:description\" content=\"B\u00f6lgesel kanser tedavileri nelerdir ve nas\u0131l yard\u0131mc\u0131 olurlar? \u0130leri kanser, \u00f6zellikle karaci\u011fer ve akci\u011ferler gibi v\u00fccudun hayatta kalmas\u0131 i\u00e7in gerekli olan hayati organlara yay\u0131ld\u0131\u011f\u0131nda tedavi edilmesi zor olabilir. 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