{"id":21514,"date":"2022-01-09T23:13:24","date_gmt":"2022-01-09T20:13:24","guid":{"rendered":"https:\/\/zdmaa.com\/the-difference-between-hodgkin-non-hodgkin-lymphoma\/"},"modified":"2022-01-11T12:44:14","modified_gmt":"2022-01-11T09:44:14","slug":"the-difference-between-hodgkin-non-hodgkin-lymphoma","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/tr\/the-difference-between-hodgkin-non-hodgkin-lymphoma\/","title":{"rendered":"Hodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark"},"content":{"rendered":"

Hodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark<\/span><\/span><\/span><\/a><\/p>\n

\n

Ortak bir k\u00f6ken, benzer semptomlar ve ortak bir adla, Hodgkin lenfomas\u0131n\u0131 Hodgkin olmayan lenfoma ile kar\u0131\u015ft\u0131rmak kolayd\u0131r. <\/span>Her iki kanser t\u00fcr\u00fc de v\u00fccudun B lenfositleri ad\u0131 verilen beyaz kan h\u00fccrelerini g\u00f6nderen lenf d\u00fc\u011f\u00fcmleri a\u011f\u0131 olan lenfatik sistemde ba\u015flar ve bu h\u00fccreler enfeksiyonla sava\u015fmam\u0131za yard\u0131mc\u0131 olan antikorlar \u00fcretir. <\/span>Herhangi bir kanser t\u00fcr\u00fc olan hastalar a\u015f\u0131r\u0131 yorgunluk, kilo kayb\u0131, i\u015ftah, ate\u015f, terleme ve di\u011fer yayg\u0131n semptomlar ya\u015fayabilir. <\/span>Her ikisinin de ad\u0131, hastal\u0131klar\u0131n semptomlar\u0131n\u0131 kaydeden \u00f6nc\u00fc ara\u015ft\u0131rmac\u0131 Dr. Thomas Hodgkin’den geliyor. <\/span>Ama ikisi aras\u0131nda \u00f6nemli farklar var.<\/span><\/span><\/p>\n

Hodgkin olmayan lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki ana tan\u0131sal fark, biyopsi s\u0131ras\u0131nda, genellikle etkilenen lenf d\u00fc\u011f\u00fcm\u00fcnden belirlenebilir. <\/span>Patolog biyopside Reed-Sternberg h\u00fccrelerini tespit ederse hastaya Hodgkin lenfoma te\u015fhisi konur. <\/span>Ad\u0131n\u0131, onlar\u0131 mikroskop alt\u0131nda ilk tan\u0131mlayan iki bilim insan\u0131ndan alan Reed-Sternberg h\u00fccreleri, sitolojik standartlara g\u00f6re normal lenfositlerden be\u015f kat daha b\u00fcy\u00fck olan devasa mutant B h\u00fccreleridir. <\/span>Bu h\u00fccrelerin yayg\u0131n bir \u00e7e\u015fidi, onlara bayku\u015f g\u00f6z\u00fc g\u00f6r\u00fcn\u00fcm\u00fc veren en az iki \u00e7ekirdek i\u00e7erir. <\/span>Di\u011fer bir t\u00fcr, lob\u00fcler \u015fekli nedeniyle patlam\u0131\u015f m\u0131s\u0131r h\u00fccresi olarak adland\u0131r\u0131l\u0131r. <\/span>Reed-Sternberg h\u00fccrelerinin farkl\u0131 \u015fekilleri, patologlar\u0131n spesifik Hodgkin lenfoma tipini tan\u0131mlamas\u0131na yard\u0131mc\u0131 olabilir.<\/span><\/span><\/p>\n

Temel Farkl\u0131l\u0131klar<\/span><\/span><\/h2>\n

\u0130ki hastal\u0131\u011f\u0131 birbirinden ay\u0131ran ba\u015fka bir\u00e7ok farkl\u0131l\u0131k vard\u0131r. <\/span>\u00d6rne\u011fin:<\/span><\/span><\/p>\n\n\n\n\n\n\n\n\n
Hodgkin lenfoma<\/span><\/span><\/th>\nNon-Hodgkin lenfoma<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
Hodgkin lenfoma te\u015fhisi konan hastalar\u0131n %32’si 20 ile 34 ya\u015flar\u0131 aras\u0131ndad\u0131r. <\/span>Hastal\u0131\u011f\u0131 olan bir hastan\u0131n ortalama ya\u015f\u0131 39’dur.<\/span><\/span><\/td>\nHodgkin lenfoma te\u015fhisi konan hastalar\u0131n y\u00fczde yetmi\u015f be\u015fi 55 ya\u015f ve \u00fczerindedir. <\/span>Hastal\u0131\u011f\u0131 olan bir hastan\u0131n ya\u015f ortalamas\u0131 66’d\u0131r.<\/span><\/span><\/td>\n<\/tr>\n
Hodgkin lenfoma nadirdir ve yeni te\u015fhis edilen t\u00fcm kanserlerin yakla\u015f\u0131k y\u00fczde 0,5’ini olu\u015fturur. <\/span>2016 y\u0131l\u0131nda tahmini 8500 vaka te\u015fhis edildi.<\/span><\/span><\/td>\nHodgkin d\u0131\u015f\u0131 lenfoma, 2016 y\u0131l\u0131nda 72.500 vakan\u0131n tahmini insidans\u0131 ile en s\u0131k te\u015fhis edilen yedinci kanserdir.<\/span><\/span><\/td>\n<\/tr>\n
Hodgkin lenfoma te\u015fhisi konan hastalar\u0131n y\u00fczde 86’s\u0131ndan fazlas\u0131 be\u015f y\u0131l veya daha fazla ya\u015f\u0131yor.<\/span><\/span><\/td>\nHodgkin d\u0131\u015f\u0131 lenfoma te\u015fhisi konan ki\u015filerin yakla\u015f\u0131k y\u00fczde 70’i be\u015f y\u0131l veya daha fazla hayatta kal\u0131r.<\/span><\/span><\/td>\n<\/tr>\n
Alt\u0131 tip Hodgkin lenfoma vard\u0131r. <\/span>En yayg\u0131n formlar\u0131 klasik nod\u00fcler skleroz Hodgkin lenfoma ve klasik mikst h\u00fccreli Hodgkin lenfomad\u0131r. <\/span>T\u00fcm vakalar\u0131n yakla\u015f\u0131k y\u00fczde 90’\u0131n\u0131 olu\u015fturuyorlar.<\/span><\/span><\/td>\nHodgkin d\u0131\u015f\u0131 lenfoman\u0131n 61’den fazla t\u00fcr\u00fc ve alt tipi vard\u0131r. <\/span>B h\u00fccreli lenfomalar, t\u00fcm vakalar\u0131n y\u00fczde 85’ini olu\u015fturur. <\/span>Diff\u00fcz b\u00fcy\u00fck B h\u00fccreli lenfoma, Hodgkin d\u0131\u015f\u0131 lenfoman\u0131n en yayg\u0131n \u015feklidir.<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

\u0627\u0644\u0645\u0635\u0627\u062f\u0631: Ulusal Kanser Enstit\u00fcs\u00fc ve Lenfoma Ara\u015ft\u0131rma Vakf\u0131<\/span><\/span><\/span><\/span><\/p>\n

\u0130ngiliz bir patolog olan Hodgkin, hastal\u0131\u011f\u0131n baz\u0131 semptomlar\u0131n\u0131 ilk olarak, geni\u015flemi\u015f lenf nodlar\u0131 ve dala\u011f\u0131 olan \u00e7e\u015fitli hastalar\u0131n \u00f6l\u00fcm sonras\u0131 muayenelerini detayland\u0131ran 1832 tarihli bir makalesinde tan\u0131mlad\u0131. <\/span>Otuz y\u0131l sonra, ba\u015fka bir \u0130ngiliz doktor olan Dr. Samuel Wilkes, benzer ara\u015ft\u0131rmalar yaparken Hodgkin’in \u00e7al\u0131\u015fmalar\u0131n\u0131 \u00f6\u011frendi. <\/span>Bu duruma Hodgkin hastal\u0131\u011f\u0131 ad\u0131 verildi. <\/span>O zamandan beri hastal\u0131k m\u00fclkiyetini kaybetti ve Hodgkin hastal\u0131\u011f\u0131 veya Hodgkin lenfoma olarak adland\u0131r\u0131ld\u0131. <\/span>Hodgkin’in ke\u015fiflerinden on y\u0131llar sonra, ara\u015ft\u0131rmac\u0131lar lenfomalar\u0131n iki farkl\u0131 tipte s\u0131n\u0131fland\u0131r\u0131labilece\u011fini daha iyi anlayabildiler: Hodgkin ve benzer fakat \u00f6nemli \u00f6l\u00e7\u00fcde farkl\u0131 bir tip, Hodgkin de\u011fil.<\/span><\/span><\/p>\n

Lenfoma tedavileri<\/span><\/span><\/h2>\n

Her iki hastal\u0131k da kemoterapi, radyoterapi ve\/veya k\u00f6k h\u00fccre nakli ile tedavi edilebilir. <\/span>Hodgkin d\u0131\u015f\u0131 lenfoma tedavisi i\u00e7in radyasyon tedavisi veya kemoterapi ile tedaviye y\u00f6nelik <\/span>Tiuxetan Ibritumomab (Zevalin <\/span><\/span>\u00ae<\/span><\/span><\/sup> ) veya monoklonal antikor (Ratutxan <\/span><\/span>\u00ae<\/span><\/span><\/sup> ) <\/span>gibi ila\u00e7lar <\/span>. <\/span>Bir kontrol noktas\u0131 inhibit\u00f6r\u00fc olarak bilinen bir imm\u00fcnoterapi ilac\u0131 olan <\/span>Nivolumab (Opdivo <\/span><\/span>\u00ae<\/span><\/span><\/sup> ), Hodgkin lenfoma tedavisi i\u00e7in onaylanm\u0131\u015ft\u0131r. <\/span>Aral\u0131k 2016’da G\u0131da ve \u0130la\u00e7 \u0130daresi Departman\u0131 , <\/span>pembrolizumab noktalar\u0131n\u0131n (Keytruda <\/span>\u00ae)<\/span><\/sup> \u00f6nleyici incelemesi i\u00e7in \u00f6ncelikli inceleme izni verdi.<\/span><\/span>) Hodgkin lenfoma tedavisi i\u00e7in. <\/span>\u0130mm\u00fcnoterapi ila\u00e7lar\u0131n\u0131n Hodgkin d\u0131\u015f\u0131 lenfoma ve multipl miyelom gibi di\u011fer hematolojik malignitelerin tedavisine de yard\u0131mc\u0131 olup olamayaca\u011f\u0131n\u0131 belirlemek i\u00e7in \u00e7ok say\u0131da klinik \u00e7al\u0131\u015fma devam etmektedir. <\/span>Amerika Kanser Tedavi Merkezlerinde t\u0131p ve bilim \u015fefi Dr. Murray Markman, “Erken veriler, imm\u00fcnoterapinin gelecekte lenfomalar\u0131n y\u00f6netiminde bir rol oynayaca\u011f\u0131n\u0131 g\u00f6steriyor” diyor. <\/span><\/span>\u00ae<\/span><\/span><\/sup> (CTCA).<\/span><\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Hodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark Ortak bir k\u00f6ken, benzer semptomlar ve ortak bir adla, Hodgkin lenfomas\u0131n\u0131 Hodgkin olmayan lenfoma ile kar\u0131\u015ft\u0131rmak kolayd\u0131r. Her iki kanser t\u00fcr\u00fc de v\u00fccudun B lenfositleri ad\u0131 verilen beyaz kan h\u00fccrelerini g\u00f6nderen lenf d\u00fc\u011f\u00fcmleri a\u011f\u0131 olan lenfatik sistemde ba\u015flar ve bu h\u00fccreler enfeksiyonla sava\u015fmam\u0131za yard\u0131mc\u0131 olan antikorlar \u00fcretir. …<\/p>\n","protected":false},"author":1,"featured_media":19950,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-21514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-tr"],"yoast_head":"\nHodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark - zdmaa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zdmaa.com\/tr\/the-difference-between-hodgkin-non-hodgkin-lymphoma\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark - zdmaa\" \/>\n<meta property=\"og:description\" content=\"Hodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark Ortak bir k\u00f6ken, benzer semptomlar ve ortak bir adla, Hodgkin lenfomas\u0131n\u0131 Hodgkin olmayan lenfoma ile kar\u0131\u015ft\u0131rmak kolayd\u0131r. Her iki kanser t\u00fcr\u00fc de v\u00fccudun B lenfositleri ad\u0131 verilen beyaz kan h\u00fccrelerini g\u00f6nderen lenf d\u00fc\u011f\u00fcmleri a\u011f\u0131 olan lenfatik sistemde ba\u015flar ve bu h\u00fccreler enfeksiyonla sava\u015fmam\u0131za yard\u0131mc\u0131 olan antikorlar \u00fcretir. …\" \/>\n<meta property=\"og:url\" content=\"https:\/\/zdmaa.com\/tr\/the-difference-between-hodgkin-non-hodgkin-lymphoma\/\" \/>\n<meta property=\"og:site_name\" content=\"zdmaa\" \/>\n<meta property=\"article:published_time\" content=\"2022-01-09T20:13:24+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-01-11T09:44:14+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/zdmaa.com\/wp-content\/uploads\/2022\/01\/lemon-g903d305fb_640.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"427\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Yazan:\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tahmini okuma s\u00fcresi\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 dakika\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/zdmaa.com\/tr\/the-difference-between-hodgkin-non-hodgkin-lymphoma\/\",\"url\":\"https:\/\/zdmaa.com\/tr\/the-difference-between-hodgkin-non-hodgkin-lymphoma\/\",\"name\":\"Hodgkin lenfoma ve Hodgkin olmayan lenfoma aras\u0131ndaki fark - 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