{"id":24164,"date":"2022-01-12T17:53:44","date_gmt":"2022-01-12T14:53:44","guid":{"rendered":"https:\/\/zdmaa.com\/how-does-immune-system-work-when-it-comes-to-cancer\/"},"modified":"2022-01-13T00:50:49","modified_gmt":"2022-01-12T21:50:49","slug":"how-does-immune-system-work-when-it-comes-to-cancer","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/tr\/how-does-immune-system-work-when-it-comes-to-cancer\/","title":{"rendered":"Kanser oldu\u011funda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi nas\u0131l \u00e7al\u0131\u015f\u0131r?"},"content":{"rendered":"

Kanser oldu\u011funda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi nas\u0131l \u00e7al\u0131\u015f\u0131r?<\/span><\/span><\/span><\/span><\/p>\n

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Her g\u00fcn\u00fcn her dakikas\u0131n\u0131n her saniyesi, bedeninizin i\u00e7inde iyi ve k\u00f6t\u00fc aras\u0131nda bir sava\u015f ba\u015flar. <\/span>\u0130yi haber, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi, v\u00fccudu hastal\u0131k ve enfeksiyondan korumak i\u00e7in tasarlanm\u0131\u015f h\u00fccre ordular\u0131. <\/span>K\u00f6t\u00fcl\u00fck, patojenler, vir\u00fcsler, bakteriler ve zarar vermeye programlanm\u0131\u015f mutasyona u\u011fram\u0131\u015f h\u00fccreler bi\u00e7iminde gelir. <\/span>Yenge\u00e7 s\u00f6z konusu oldu\u011funda, iyi adamlar her zaman kazanmaz. <\/span>Ancak yeni imm\u00fcnoterapiler, geli\u015fen teknolojiler ve devam eden ara\u015ft\u0131rmalar, klinisyenlere ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin yapmas\u0131 gereken i\u015fi yapmas\u0131na yard\u0131mc\u0131 olacak daha fazla ara\u00e7 sa\u011fl\u0131yor: kanser gibi tehditlerle m\u00fccadele. <\/span>Kanser ara\u015ft\u0131rmac\u0131lar\u0131, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin nas\u0131l \u00e7al\u0131\u015ft\u0131\u011f\u0131, kanserin ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinden nas\u0131l sakland\u0131\u011f\u0131 ve belirli ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin kanserin b\u00fcy\u00fcmesine ger\u00e7ekten nas\u0131l yard\u0131mc\u0131 oldu\u011fu hakk\u0131nda daha fazla bilgi edindik\u00e7e \u00e7evrimi\u00e7i olarak daha fazla geli\u015fme oluyor. <\/span>Ke\u015ffettikleri \u015fey, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin v\u00fccudu koruyan ve baz\u0131 durumlarda kanserin onu yok etmesine yard\u0131mc\u0131 olan karma\u015f\u0131k bir sistem oldu\u011fudur.<\/span><\/span><\/p>\n

Phoenix yak\u0131nlar\u0131ndaki hastanemizde resepsiyonist ve birinci basamak hekimi olan Stephen Lynch, \u201cBa\u011f\u0131\u015f\u0131kl\u0131k sistemi kanserle m\u00fccadelede kritik \u00f6neme sahiptir\u201d diyor. <\/span>“Bize zarar verebilecek orijinal ve yerli olmayan h\u00fccreleri tan\u0131mak i\u00e7in tasarlanm\u0131\u015f bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemimiz var. Sorun \u015fu ki her zaman \u00e7al\u0131\u015fm\u0131yor. Di\u011fer zamanlarda bize kar\u015f\u0131 \u00e7al\u0131\u015f\u0131yor.”<\/span><\/span><\/p>\n

Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi verimli ve g\u00fc\u00e7l\u00fc bir biyolojik makinedir. <\/span>Kesinlikle milyonlarca mikroptan ve vir\u00fcs ve enfeksiyonlarla sava\u015f\u0131r. <\/span>Tepkileri o kadar g\u00fc\u00e7l\u00fcd\u00fcr ki ate\u015f, a\u011fr\u0131 ve s\u0131z\u0131lara, iltihaplanmaya ve \u015fi\u015fmeye neden olabilirler. <\/span>Dr. Lynch, “Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminiz geli\u015fti\u011fi i\u00e7in yapmas\u0131 gerekeni yap\u0131yor” diyor. <\/span>Ve yapt\u0131\u011f\u0131 \u015fey hastal\u0131klarla sava\u015fmaktan daha fazlas\u0131. <\/span>Northwestern \u00dcniversitesi’ndeki ara\u015ft\u0131rmac\u0131lar, makrofajlar olarak bilinen ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin kalp kas\u0131 h\u00fccrelerini uyard\u0131\u011f\u0131, bu da kalbin atmas\u0131n\u0131 ve sabit bir at\u0131m\u0131 s\u00fcrd\u00fcrmesine yard\u0131mc\u0131 oldu\u011fu sonucuna var\u0131yor. <\/span>\u0130sve\u00e7li ara\u015ft\u0131rmac\u0131lar ayr\u0131ca, ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerinin fel\u00e7ten sonra \u00f6l\u00fc beyin h\u00fccrelerini \u00f6ld\u00fcrd\u00fc\u011f\u00fcne ve beynin hasar\u0131 onarmas\u0131na izin verebilecek maddeler salg\u0131lad\u0131\u011f\u0131na dair kan\u0131tlar buldu. <\/span>Bununla birlikte, ayn\u0131 zamanda bilim adamlar\u0131, kanser h\u00fccrelerinin yaln\u0131zca ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin savunmas\u0131ndan ka\u00e7makla kalmay\u0131p, asl\u0131nda v\u00fccuda sald\u0131r\u0131lar\u0131n\u0131 kolayla\u015ft\u0131rmak i\u00e7in ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini nas\u0131l kulland\u0131klar\u0131n\u0131 \u00f6\u011freniyorlar.<\/span><\/span><\/p>\n

askeri hassasiyet<\/span><\/span><\/h2>\n

Askeri terimlerle, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi iki b\u00f6l\u00fcmden olu\u015fur: do\u011fu\u015ftan gelen ve edinilmi\u015f. <\/span>Her b\u00f6l\u00fcm i\u00e7inde, spesifik ba\u011f\u0131\u015f\u0131kl\u0131k fonksiyonlar\u0131n\u0131 yerine getiren farkl\u0131 h\u00fccre sistemleri bulunur. <\/span>Do\u011fu\u015ftan gelen ba\u011f\u0131\u015f\u0131kl\u0131k, v\u00fccudun ilk savunma hatt\u0131d\u0131r. <\/span>Bu ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri, konak\u00e7\u0131 i\u00e7in bir tehdit olarak alg\u0131lad\u0131klar\u0131 h\u00fccrelere sald\u0131rmak \u00fczere programlanm\u0131\u015ft\u0131r. <\/span>New York’taki Perlmutter Kanser Merkezi’nin m\u00fcd\u00fcr yard\u0131mc\u0131s\u0131 Dr. Jeffrey Weber, “\u00d6nce do\u011fu\u015ftan gelen ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri \u00f6ld\u00fcr\u00fcl\u00fcr ve sorular daha sonra sorulur” diye \u015faka yapt\u0131. <\/span>Do\u011fu\u015ftan gelen ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin h\u00fccreleri \u015funlar\u0131 i\u00e7erir:<\/span><\/span><\/p>\n

Makrofajlar:<\/span><\/span><\/strong> Ad\u0131n\u0131 “b\u00fcy\u00fck yiyiciler” anlam\u0131na gelen Yunanca s\u00f6zc\u00fcklerden alan bu uzun \u00f6m\u00fcrl\u00fc h\u00fccreler takma adlar\u0131na sad\u0131kt\u0131r. <\/span>Oburdurlar ve hedeflerine ba\u011flanmak ve sald\u0131rmak i\u00e7in esnek dallar kullan\u0131rlar.<\/span><\/span><\/p>\n

N\u00f6trofiller:<\/span><\/span><\/strong> Bu k\u0131sa \u00f6m\u00fcrl\u00fc h\u00fccreler, enfeksiyona kar\u015f\u0131 ilk savunma hatt\u0131d\u0131r. <\/span>Bakterileri \u00f6ld\u00fcr\u00fcrler ve sonra \u00f6l\u00fcrler ve irin olu\u015ftururlar.<\/span><\/span><\/p>\n

K\u00f6k h\u00fccreler:<\/span><\/span><\/strong> Bunlar, T h\u00fccrelerini ve B h\u00fccrelerini hedeflerine y\u00f6nlendiren, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin do\u011fu\u015ftan gelen trafik polisleridir.<\/span><\/span><\/p>\n

Mast h\u00fccreleri ve bazofiller:<\/span><\/span><\/strong> Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin alerjenlere sald\u0131rmas\u0131na yard\u0131mc\u0131 olan histaminler \u00fcretirler.<\/span><\/span><\/p>\n

Do\u011fal \u00f6ld\u00fcr\u00fcc\u00fc (NK)<\/span><\/span><\/strong> h\u00fccreler <\/span>:<\/span><\/strong> Bu duyarl\u0131 h\u00fccreler vir\u00fcslere sald\u0131r\u0131r ve kanser \u00f6ncesi h\u00fccrelere ve kanser h\u00fccrelerine sald\u0131rmada agresif olabilir.<\/span><\/span><\/p>\n

Edinilmi\u015f ba\u011f\u0131\u015f\u0131kl\u0131k olarak da adland\u0131r\u0131lan kazan\u0131lm\u0131\u015f ba\u011f\u0131\u015f\u0131kl\u0131k sistemi daha geli\u015fmi\u015ftir ve bir sald\u0131r\u0131 plan\u0131 geli\u015ftirmesi daha uzun s\u00fcrer. <\/span>Adaptif ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri \u015funlard\u0131r:<\/span><\/span><\/p>\n

B h\u00fccreleri:<\/span><\/span><\/strong> Kemik ili\u011finde geli\u015fir ve olgunla\u015f\u0131rlar ve vir\u00fcsler ve bakterilerle sava\u015fan antikor ad\u0131 verilen proteinler \u00fcretirler.<\/span><\/span><\/p>\n

T h\u00fccreleri: Ayr\u0131ca<\/span><\/span><\/strong> kemik ili\u011finde olu\u015furlar ancak timusta olgunla\u015f\u0131rlar. <\/span>\u0130ki ana T h\u00fccresi t\u00fcr\u00fc vard\u0131r: B h\u00fccrelerini antikor \u00fcretmesi i\u00e7in uyaran yard\u0131mc\u0131 T h\u00fccreleri ve h\u00fccrelere do\u011frudan sald\u0131ran \u00f6ld\u00fcr\u00fcc\u00fc T h\u00fccreleri.<\/span><\/span><\/p>\n

Adaptif ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri, dendritik h\u00fccreler ve di\u011fer mantar h\u00fccreleri taraf\u0131ndan sa\u011flanan bilgileri kullanarak vir\u00fcsleri veya bakterileri hedefler ve bu patojenler hakk\u0131nda bilgi depolar, b\u00f6ylece ba\u015fka bir sald\u0131r\u0131 ba\u015flat\u0131rlarsa onlar\u0131 tan\u0131mlay\u0131p tekrar sald\u0131rabilirler.<\/span><\/span><\/p>\n

d\u00f6n\u00fcm noktas\u0131<\/span><\/span><\/h2>\n

Fakat ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bu kadar g\u00fc\u00e7l\u00fc ve geli\u015fmi\u015fse, kanserle m\u00fccadelede neden \u00e7o\u011fu zaman ba\u015far\u0131s\u0131z oluyor? <\/span>K\u0131sa cevap: \u00c7\u00fcnk\u00fc kanser onu kontrol ediyor. <\/span>Phoenix yak\u0131nlar\u0131ndaki hastanemizde hematoloji ve imm\u00fcnoterapi t\u0131bbi direkt\u00f6r\u00fc ve bir onkolog ve hematolog olan Alan Tan, “Hastalar\u0131ma bir ba\u011f\u0131\u015f\u0131kl\u0131k sistemimiz yoksa hepimizin kanser olaca\u011f\u0131n\u0131 s\u00f6yl\u00fcyorum” diyor. <\/span>“H\u00fccresel mutasyonun y\u00fck\u00fc ile ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin onunla ne kadar iyi sava\u015fabilece\u011fi aras\u0131nda hassas bir denge var. Tehditlere kar\u015f\u0131 her zaman tetikte. Ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemi bir t\u00fcm\u00f6r\u00fc bast\u0131rd\u0131\u011f\u0131nda, t\u00fcm\u00f6r\u00fc tan\u0131y\u0131p yan\u0131t veremiyor. tehdit.”<\/span><\/span><\/p>\n

Asl\u0131nda, ba\u011f\u0131\u015f\u0131kl\u0131k sisteminizin sizin bilginiz olmadan kanser veya kanser \u00f6ncesi ko\u015fullarla d\u00fczenli olarak sava\u015fabilmesi m\u00fcmk\u00fcnd\u00fcr, hatta muhtemeldir. <\/span>Tan, “Hepimiz, v\u00fccutta g\u00f6r\u00fcn\u00fcr kanser geli\u015ftirmemizi \u00f6nlemek i\u00e7in az say\u0131da kanser h\u00fccresini filtreleyen bir mekanizmaya sahibiz” diyor ve “Zamanla bu denge bozuluyor.”<\/span><\/span><\/p>\n

Kanserin ba\u011f\u0131\u015f\u0131kl\u0131k sistemini alt etmeye ba\u015flad\u0131\u011f\u0131 ta\u015fma noktas\u0131 her zaman bilinmemektedir. <\/span>Dr. Lynch, “Olabilecek bir\u00e7ok farkl\u0131 neden var” diyor. <\/span>“T\u00fcm\u00f6r\u00fcn DNA’s\u0131yla ilgili bir \u015fey. Kanserin g\u00fcc\u00fcyle ilgili bir \u015fey.” <\/span>Ancak ara\u015ft\u0131rmalar, kanser h\u00fccrelerinin belirli do\u011fu\u015ftan gelen ve uyarlanabilir ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccreleri \u00fczerinde muazzam bir etkiye sahip oldu\u011funu ve onlar\u0131 kanserin b\u00fcy\u00fcmesine ve seyahat etmesine yard\u0131mc\u0131 olmak i\u00e7in i\u015fe ald\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. <\/span>Augusta \u00dcniversitesi Georgia Kanser Merkezi’nden ara\u015ft\u0131rmac\u0131lar, kanser h\u00fccrelerinin \u00e7o\u011falmak i\u00e7in kemik ili\u011fi kaynakl\u0131 bask\u0131lay\u0131c\u0131 h\u00fccreler (MDSC) ad\u0131 verilen olgunla\u015fmam\u0131\u015f ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini kulland\u0131\u011f\u0131na dair kan\u0131tlar bulduklar\u0131n\u0131 bildirdiler. <\/span>Yan\u0131lt\u0131c\u0131 sinyaller kullanarak kanser h\u00fccreleri, MDSC’lerin b\u00fcy\u00fcmesini engeller ve bunlar\u0131 t\u00fcm\u00f6rlerin yay\u0131lmas\u0131na yard\u0131mc\u0131 olmak i\u00e7in kullan\u0131r. <\/span>Georgia Kanser Merkezi’nden Dr. Hasan Kurkaya, “Bu h\u00fccreler kanserin ba\u015far\u0131l\u0131 bir \u015fekilde yay\u0131lmas\u0131 i\u00e7in gereklidir” dedi. <\/span><\/span>G\u00fcnl\u00fck bilim <\/span><\/span><\/em>.<\/span><\/span><\/em> “Ba\u011f\u0131\u015f\u0131kl\u0131k sisteminde genellikle anti-t\u00fcm\u00f6r olan \u00e7ok karma\u015f\u0131k bir denge vard\u0131r, yani t\u00fcm\u00f6rleri \u00f6ld\u00fcr\u00fcr, ancak baz\u0131 durumlarda bu denge bozulursa, bu h\u00fccreler t\u00fcm\u00f6rlerin b\u00fcy\u00fcmesine ve metastatik hastal\u0131k haline gelmesine yard\u0131mc\u0131 olabilir.”<\/span><\/span><\/p>\n

ba\u011f\u0131\u015f\u0131kl\u0131k sistemini uyarmak<\/span><\/span><\/h2>\n

Nature’daki<\/span><\/span><\/em> bir makale, <\/span>t\u00fcm\u00f6rle ili\u015fkili makrofajlar\u0131n (TAM’ler) meme t\u00fcm\u00f6rlerinin olu\u015fumuna nas\u0131l yard\u0131mc\u0131 oldu\u011funu a\u00e7\u0131klar. <\/span>Makrofajlar genellikle baz\u0131 meme t\u00fcm\u00f6rlerinde \u00e7ok say\u0131da bulunur. <\/span>Kanser h\u00fccrelerine sald\u0131rabilseler de, “g\u00f6\u011f\u00fcs t\u00fcm\u00f6rlerindeki makrofajlar, t\u00fcm\u00f6r b\u00fcy\u00fcmesini ve metastaz\u0131 te\u015fvik etmek i\u00e7in istenmeyen bir lisansa sahiptir.” <\/span>Makalenin <\/span><\/span>mizac\u0131n\u0131n niteli\u011fini<\/span><\/span><\/em> s\u00f6yl\u00fcyor. <\/span>Albert Einstein T\u0131p Fak\u00fcltesi’ndeki ara\u015ft\u0131rmac\u0131lar ve \u00f6\u011frenciler, s\u00fcreci videoya kaydettiklerini bildirdiler. <\/span>Film, kanser h\u00fccrelerinin kan dola\u015f\u0131m\u0131na girmesine yard\u0131mc\u0131 olmak i\u00e7in birlikte \u00e7al\u0131\u015fan farelerdeki makrofajlar\u0131 ve meme kanseri h\u00fccrelerini g\u00f6steriyor.<\/span><\/span><\/p>\n

Ara\u015ft\u0131rmalar, TAM’leri ve di\u011fer do\u011fu\u015ftan gelen h\u00fccreleri hedef alan bir imm\u00fcnoterapi ilac\u0131n\u0131n, ba\u011f\u0131\u015f\u0131kl\u0131k sistemini t\u00fcm\u00f6rlere sald\u0131rmas\u0131 i\u00e7in uyarabilece\u011fini d\u00fc\u015f\u00fcnd\u00fcrmektedir. <\/span>Dana-Farber Kanser Enstit\u00fcs\u00fcndeki doktorlar, kanser h\u00fccrelerine sald\u0131rmak i\u00e7in TAM’leri yeniden etkinle\u015ftirmek i\u00e7in tasarlanm\u0131\u015f TMP195 adl\u0131 bir bile\u015fi\u011fi tar\u0131yor. <\/span>Ara\u015ft\u0131rmalar, bu i\u015flemin farelerde meme kanseri t\u00fcm\u00f6rlerini azaltt\u0131\u011f\u0131n\u0131 g\u00f6stermi\u015ftir. <\/span>2015 y\u0131l\u0131nda FDA <\/span>, multipl miyelomu tedavi etmek i\u00e7in bir <\/span>imm\u00fcn sistemi uyar\u0131c\u0131 <\/span>ila\u00e7 olarak <\/span>kabul edilen elotuzumab’\u0131 (Empliciti <\/span><\/span>\u2122<\/span><\/span><\/sub> ) <\/span>onaylad\u0131 <\/span>. <\/span>Tan, “Bu ila\u00e7 yaln\u0131zca \u00e7oklu miyelom h\u00fccrelerini hedef almakla kalm\u0131yor, ayn\u0131 zamanda do\u011fal \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccreleri de g\u00fc\u00e7lendiriyor” diyor Dr. Tan, “Miyelom h\u00fccreleri do\u011fal \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccreleri bask\u0131layabilir. Ancak miyelom h\u00fccre pop\u00fclasyonu azald\u0131k\u00e7a do\u011fal \u00f6ld\u00fcr\u00fcc\u00fc h\u00fccrelerin say\u0131s\u0131 ve i\u015flevi de azal\u0131r “<\/span><\/span><\/p>\n

Ara\u015ft\u0131rmac\u0131lar, do\u011fu\u015ftan gelen ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini yeniden \u015farj eden imm\u00fcnoterapi ila\u00e7lar\u0131 \u00fczerinde \u00e7al\u0131\u015fmaya devam ettik\u00e7e, adaptif ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin \u00f6nemli bir bile\u015feni olan T h\u00fccrelerini aktive eden ila\u00e7lar\u0131n geli\u015ftirilmesinde \u00f6nemli ilerleme kaydedilmi\u015ftir. <\/span>A\u011fustos ay\u0131nda, ABD G\u0131da ve \u0130la\u00e7 \u0130daresi, kimerik antijen resept\u00f6r\u00fc (CAR) T h\u00fccreleri ad\u0131 verilen modifiye edilmi\u015f ba\u011f\u0131\u015f\u0131kl\u0131k h\u00fccrelerini kullanan ilk evlat edinen h\u00fccre transfer tedavisini onaylad\u0131. <\/span>Bu h\u00fccreler, bir gen ile modifiye edilmi\u015f, laboratuvarda milyarlarca ki\u015fi taraf\u0131ndan \u00fcretilen ve daha sonra belirli kanser h\u00fccrelerine sald\u0131rmak i\u00e7in hastaya geri enjekte edilen hastan\u0131n kendi T h\u00fccrelerini kullan\u0131r. <\/span>Tedavi, akut lenfositik l\u00f6semili gen\u00e7 hastalar i\u00e7in onayland\u0131 ve devam eden ara\u015ft\u0131rmalar, di\u011fer s\u0131v\u0131 kanserleri tedavi etmek i\u00e7in kullan\u0131l\u0131p kullan\u0131lamayaca\u011f\u0131n\u0131 ara\u015ft\u0131r\u0131yor.<\/span><\/span><\/p>\n

Kanser h\u00fccrelerini do\u011frudan \u00f6ld\u00fcren kemoterapi ve radyoterapiden farkl\u0131 olarak, imm\u00fcnoterapi ila\u00e7lar\u0131 kanser h\u00fccrelerine sald\u0131rmaz, aksine v\u00fccudun g\u00fc\u00e7l\u00fc ba\u011f\u0131\u015f\u0131kl\u0131k sistemini harekete ge\u00e7irir. <\/span>Dr. Lynch, “Ba\u011f\u0131\u015f\u0131kl\u0131k sistemi kanserle m\u00fccadelede \u00e7ok \u00f6nemlidir” diyor. <\/span>“\u0130mm\u00fcnoterapi, oraya gidip kanser h\u00fccrelerini \u00f6ld\u00fcrmekle ilgili de\u011fildir. Sadece saklamaya \u00e7al\u0131\u015ft\u0131\u011f\u0131 kanser h\u00fccresinin maskesini kald\u0131r\u0131r ve ba\u011f\u0131\u015f\u0131kl\u0131k sisteminin onu tan\u0131mas\u0131n\u0131 ve tasarland\u0131\u011f\u0131 i\u015fi yapmas\u0131n\u0131 sa\u011flar.”<\/span><\/span><\/p>\n

\u0130mm\u00fcnoterapi hakk\u0131nda daha fazla bilgi edinin.<\/span><\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Kanser oldu\u011funda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi nas\u0131l \u00e7al\u0131\u015f\u0131r? Her g\u00fcn\u00fcn her dakikas\u0131n\u0131n her saniyesi, bedeninizin i\u00e7inde iyi ve k\u00f6t\u00fc aras\u0131nda bir sava\u015f ba\u015flar. \u0130yi haber, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi, v\u00fccudu hastal\u0131k ve enfeksiyondan korumak i\u00e7in tasarlanm\u0131\u015f h\u00fccre ordular\u0131. K\u00f6t\u00fcl\u00fck, patojenler, vir\u00fcsler, bakteriler ve zarar vermeye programlanm\u0131\u015f mutasyona u\u011fram\u0131\u015f h\u00fccreler bi\u00e7iminde gelir. Yenge\u00e7 s\u00f6z konusu oldu\u011funda, iyi adamlar her zaman …<\/p>\n","protected":false},"author":1,"featured_media":23442,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-24164","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-tr"],"yoast_head":"\nKanser oldu\u011funda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi nas\u0131l \u00e7al\u0131\u015f\u0131r? - zdmaa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zdmaa.com\/tr\/how-does-immune-system-work-when-it-comes-to-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kanser oldu\u011funda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi nas\u0131l \u00e7al\u0131\u015f\u0131r? - zdmaa\" \/>\n<meta property=\"og:description\" content=\"Kanser oldu\u011funda ba\u011f\u0131\u015f\u0131kl\u0131k sistemi nas\u0131l \u00e7al\u0131\u015f\u0131r? 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