{"id":24505,"date":"2022-01-12T14:21:21","date_gmt":"2022-01-12T11:21:21","guid":{"rendered":"https:\/\/zdmaa.com\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/"},"modified":"2022-01-13T12:44:25","modified_gmt":"2022-01-13T09:44:25","slug":"a-simple-blood-test-may-help-illustrate-a-patients-cancer","status":"publish","type":"post","link":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/","title":{"rendered":"Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir"},"content":{"rendered":"

Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir<\/span><\/span><\/span><\/span><\/p>\n

\n

Biyopsi, \u00e7o\u011fu kanser te\u015fhisinin temelidir ve kanser h\u00fccreleri i\u00e7in kontrol edilebilmesi i\u00e7in bir t\u00fcm\u00f6r\u00fc \u00e7\u0131karmak i\u00e7in kullan\u0131lan cerrahi prosed\u00fcrd\u00fcr. <\/span>Doktorlar, tedaviler i\u00e7in bir hedef olabilecek kanserin malignitesini, evresini, k\u00f6kenini ve DNA mutasyonlar\u0131n\u0131 de\u011ferlendirmeye yard\u0131mc\u0131 olmas\u0131 i\u00e7in s\u0131kl\u0131kla biyopsilere g\u00fcvenirler. <\/span>Baz\u0131 biyopsiler minimal invazivdir; <\/span>Di\u011ferleri daha zor olabilir ve diki\u015f veya anestezi gerektirebilir. <\/span>\u015eimdi, s\u0131v\u0131 biyopsi ad\u0131 verilen basit bir kan testi, doktorlara kat\u0131 t\u00fcm\u00f6rler hakk\u0131nda daha eksiksiz bir genel bak\u0131\u015f sunabilecek ba\u015fka bir ara\u00e7 sunuyor. <\/span>Test, cerrahi biyopsilerin yerini tutmaz, ancak belirli tedavi se\u00e7eneklerinin belirlenmesine yard\u0131mc\u0131 olacak ek bilgiler sa\u011flayabilir. <\/span>Bu son teknoloji \u015fu anda yaln\u0131zca belirli akci\u011fer kanseri t\u00fcrlerinde kullan\u0131l\u0131yor olsa da, di\u011fer kat\u0131 t\u00fcm\u00f6r modellerini izlemek ve tan\u0131mlamak i\u00e7in bir ara\u00e7 olarak ara\u015ft\u0131r\u0131l\u0131yor. <\/span>Arturo Loaiza-Bonilla, MD, MSEd, FACP diyor ki:<\/span><\/span><\/p>\n

Kanser h\u00fccresi testi<\/span><\/span><\/h2>\n

T\u00fcm\u00f6rler, genotiplerini ta\u015f\u0131yan h\u00fccreleri s\u00fcrekli olarak d\u00f6kerler. <\/span>Bu h\u00fccreler genellikle kan dola\u015f\u0131m\u0131na girer. <\/span>S\u0131v\u0131 biyopsiler, bu h\u00fccreleri izole etmek ve kanser ve t\u00fcm\u00f6r b\u00fcy\u00fcmesine yol a\u00e7abilecek mutasyonlar\u0131 g\u00f6sterebilecek belirli genetik \u00f6zellikleri aramak i\u00e7in tasarlanm\u0131\u015ft\u0131r. <\/span>Dr. Loaiza-Bonilla, “Kanserle ilgili testlerin \u00e7o\u011funda, s\u0131v\u0131 biyopsiler metastatik t\u00fcm\u00f6rlerden, yani kanser hastalar\u0131n\u0131n kan dola\u015f\u0131m\u0131ndaki k\u0131s\u0131mlardan DNA arar” diyor. <\/span>“Test, baz\u0131 par\u00e7alar\u0131n kansere \u00f6zg\u00fc mutasyonlara sahip oldu\u011funu tespit edebilir ve tedavi se\u00e7eneklerini iyile\u015ftirmek i\u00e7in hedefleyebilece\u011fimiz zay\u0131fl\u0131klar\u0131 belirlemeye yard\u0131mc\u0131 olabilir.”<\/span><\/span><\/p>\n

Ge\u00e7en y\u0131l, ABD G\u0131da ve \u0130la\u00e7 Dairesi, k\u00fc\u00e7\u00fck h\u00fccreli d\u0131\u015f\u0131 akci\u011fer kanserli baz\u0131 hastalarda bulunan bir genetik mutasyonu tespit etmek i\u00e7in ilk kan testini onaylad\u0131. <\/span>CUBA\u00ae <\/span><\/span>EGFR<\/span><\/span><\/sup> v2 mutasyon testi olarak adland\u0131r\u0131lan test, doku \u00f6rne\u011fine ihtiya\u00e7 duymadan epidermal b\u00fcy\u00fcme fakt\u00f6r\u00fc resept\u00f6r\u00fc (EGFR) genindeki mutasyonlar\u0131 belirlemek i\u00e7in tasarlanm\u0131\u015ft\u0131r. <\/span>Yak\u0131nlardaki hastanemizde hematoloji ve imm\u00fcnoterapi, onkolog ve hematolog t\u0131bbi direkt\u00f6r\u00fc Dr. Alan Tan, \u201cS\u0131v\u0131 biyopsi bu mutasyonu olduk\u00e7a h\u0131zl\u0131 ve etkili bir \u015fekilde tespit edebilir, b\u00f6ylece hasta mutasyonu hedefleyen spesifik tedaviden yararlanabilir\u201d diyor. Anka ku\u015fu. <\/span>. <\/span>.<\/span><\/span><\/p>\n

\u00c7o\u011fu durumda, s\u0131v\u0131 biyopsiler kan testlerine at\u0131fta bulunur, ancak idrar, d\u0131\u015fk\u0131 veya beyin omurilik s\u0131v\u0131s\u0131 gibi di\u011fer \u00f6rnek t\u00fcrlerini de i\u00e7erebilirler. <\/span><\/span>\u00d6rne\u011fin<\/span><\/span><\/sup> Cologard\u00ae <\/span>, baz\u0131 hastalar, \u00f6zellikle de kolorektal kanser riski daha d\u00fc\u015f\u00fck olanlar i\u00e7in kolonoskopiye alternatif sa\u011flayabilecek bir d\u0131\u015fk\u0131 testi t\u00fcr\u00fcd\u00fcr. <\/span>Dr. Tan, Cologuard’\u0131n di\u011fer s\u0131v\u0131 biyopsilerden farkl\u0131 oldu\u011funu s\u00f6yl\u00fcyor. <\/span>“Cologuard ayr\u0131ca kanser veya kanser \u00f6ncesi ile ba\u011flant\u0131l\u0131 olabilecek de\u011fi\u015ftirilmi\u015f DNA’n\u0131n y\u00fcksek seviyelerini bulmaya \u00e7al\u0131\u015f\u0131yor” dedi. <\/span>“Cologuard ile belirli s\u00fcr\u00fcc\u00fc mutasyonlar\u0131na de\u011fil, size pozitif veya negatif kanser sonucu verebilecek genetik \u00f6zelliklere bak\u0131yoruz.”<\/span><\/span><\/p>\n

Do\u011fu Virginia T\u0131p Okulu’ndaki ara\u015ft\u0131rmac\u0131larla birlikte \u00e7al\u0131\u015fan Kanadal\u0131 doktorlar, yaln\u0131zca prostat kanseri hastalar\u0131nda bulunan proteinleri tespit edebilen bir idrar testi geli\u015ftirmeye yak\u0131n olabileceklerini s\u00f6yl\u00fcyorlar. <\/span>Ara\u015ft\u0131rmac\u0131lar, testin kanserin agresif olup olmad\u0131\u011f\u0131n\u0131 da ortaya \u00e7\u0131karabilece\u011fini s\u00f6yl\u00fcyor. <\/span>Princess Margaret Kanser Merkezi’nde ba\u015f bilim adam\u0131 ve enstit\u00fcde do\u00e7ent olan ba\u015f ara\u015ft\u0131rmac\u0131 Thomas Kisslinger, “Agresif veya yava\u015f b\u00fcy\u00fcyen prostat kanserli hastalar\u0131 non-invaziv biyobelirte\u00e7ler kullanarak tahmin etmemize olanak tan\u0131yan daha iyi bir y\u00f6ntem buldu\u011fumuza inan\u0131yoruz” dedi. <\/span>Toronto <\/span><\/span>Bilim G\u00fcnl\u00fck<\/span><\/span><\/em> \u00dcniversitesi s\u00f6yledi . <\/span>“Bu, sonunda bu hastalar i\u00e7in kanser tedavisini \u00f6zelle\u015ftirmemize yard\u0131mc\u0131 olabilir.”<\/span><\/span><\/p>\n

Likit biyopsi limitleri<\/span><\/span><\/h2>\n

Ancak s\u0131v\u0131 biyopsilerin de s\u0131n\u0131rlamalar\u0131 vard\u0131r. <\/span>Baz\u0131 durumlarda, daha ayr\u0131nt\u0131l\u0131 bir te\u015fhis elde etmek i\u00e7in s\u0131v\u0131 numunesi al\u0131nd\u0131ktan sonra ek prosed\u00fcrler gerekebilir. <\/span>S\u0131v\u0131 biyopsiler, test i\u00e7in kullan\u0131labilecek kanser say\u0131s\u0131 a\u00e7\u0131s\u0131ndan da s\u0131n\u0131rl\u0131d\u0131r. <\/span>Mevcut testler \u00e7o\u011fu DNA mutasyonunu tespit etmemektedir ve baz\u0131 t\u00fcm\u00f6rler onlar\u0131 tespit etmek i\u00e7in kan dola\u015f\u0131m\u0131na yeterli miktarda h\u00fccre salg\u0131lamamaktad\u0131r.<\/span><\/span><\/p>\n

Sonunda cerrahi biyopsilere bir alternatif olarak geli\u015ftirilirse, likit biyopsinin baz\u0131 belirgin avantajlar\u0131 vard\u0131r, Dr. <\/span>Tan ve Luisa Bonilla diyor. <\/span>Dr. Tan, “En belirgin fayda, cerrahi bir prosed\u00fcr gerektirmemenin rahatl\u0131\u011f\u0131 ve g\u00fcvenli\u011fidir” diyor. <\/span>Ve metastatik kanser vakalar\u0131nda, s\u0131v\u0131 biyopsi doktorlara kanserin genel zorlu\u011fu hakk\u0131nda daha geni\u015f bir resim verebilir. <\/span>Dr. Loaiza-Bonilla, “Kanser h\u00fccreleri v\u00fccutta dola\u015f\u0131rken mutasyona u\u011fray\u0131p DNA’lar\u0131n\u0131 de\u011fi\u015ftirdikleri i\u00e7in, kan \u00f6rne\u011fi almak bize her yerden DNA par\u00e7alar\u0131n\u0131 g\u00f6sterebilir, tek b\u00f6lge biyopsisinin aksine” diyor.<\/span><\/span><\/p>\n

S\u0131v\u0131 biyopsilerin pankreas, b\u00f6brek ve yumurtal\u0131k kanserleri de dahil olmak \u00fczere \u00e7e\u015fitli kanserler i\u00e7in potansiyel bir te\u015fhis arac\u0131 olup olmayaca\u011f\u0131n\u0131 belirlemek i\u00e7in d\u00fczinelerce klinik \u00e7al\u0131\u015fma devam etmektedir. <\/span>Tan, “S\u0131v\u0131 biyopsilerin geleneksel biyopsilerin yerini al\u0131p almayaca\u011f\u0131 hen\u00fcz bilinmiyor. Klinisyenler olarak hastalar\u0131m\u0131z\u0131 invaziv prosed\u00fcrlerin gereksiz rahats\u0131zl\u0131k ve endi\u015felerine maruz b\u0131rakmak istemiyoruz. Dolay\u0131s\u0131yla bir teknik var. kaliteden \u00f6d\u00fcn vermeden d\u00fc\u015f\u00fcnmeye gerek yok.”<\/span><\/span><\/p>\n

Biyopsiler ve di\u011fer tan\u0131 ara\u00e7lar\u0131 hakk\u0131nda daha fazla bilgi edinin.<\/span><\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir Biyopsi, \u00e7o\u011fu kanser te\u015fhisinin temelidir ve kanser h\u00fccreleri i\u00e7in kontrol edilebilmesi i\u00e7in bir t\u00fcm\u00f6r\u00fc \u00e7\u0131karmak i\u00e7in kullan\u0131lan cerrahi prosed\u00fcrd\u00fcr. Doktorlar, tedaviler i\u00e7in bir hedef olabilecek kanserin malignitesini, evresini, k\u00f6kenini ve DNA mutasyonlar\u0131n\u0131 de\u011ferlendirmeye yard\u0131mc\u0131 olmas\u0131 i\u00e7in s\u0131kl\u0131kla biyopsilere g\u00fcvenirler. Baz\u0131 biyopsiler minimal invazivdir; Di\u011ferleri daha …<\/p>\n","protected":false},"author":1,"featured_media":23242,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[],"class_list":["post-24505","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-tr"],"yoast_head":"\nBasit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir - zdmaa<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir - zdmaa\" \/>\n<meta property=\"og:description\" content=\"Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir Biyopsi, \u00e7o\u011fu kanser te\u015fhisinin temelidir ve kanser h\u00fccreleri i\u00e7in kontrol edilebilmesi i\u00e7in bir t\u00fcm\u00f6r\u00fc \u00e7\u0131karmak i\u00e7in kullan\u0131lan cerrahi prosed\u00fcrd\u00fcr. 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Doktorlar, tedaviler i\u00e7in bir hedef olabilecek kanserin malignitesini, evresini, k\u00f6kenini ve DNA mutasyonlar\u0131n\u0131 de\u011ferlendirmeye yard\u0131mc\u0131 olmas\u0131 i\u00e7in s\u0131kl\u0131kla biyopsilere g\u00fcvenirler. Baz\u0131 biyopsiler minimal invazivdir; Di\u011ferleri daha …","og_url":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/","og_site_name":"zdmaa","article_published_time":"2022-01-12T11:21:21+00:00","article_modified_time":"2022-01-13T09:44:25+00:00","og_image":[{"width":507,"height":640,"url":"https:\/\/zdmaa.com\/wp-content\/uploads\/2022\/01\/syringe-g03fb6e5bf_640.png","type":"image\/png"}],"author":"admin","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"admin","Tahmini okuma s\u00fcresi":"5 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/","url":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/","name":"Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir - zdmaa","isPartOf":{"@id":"https:\/\/zdmaa.com\/tr\/ro\/#website"},"primaryImageOfPage":{"@id":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/#primaryimage"},"image":{"@id":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/#primaryimage"},"thumbnailUrl":"https:\/\/zdmaa.com\/wp-content\/uploads\/2022\/01\/syringe-g03fb6e5bf_640.png","datePublished":"2022-01-12T11:21:21+00:00","dateModified":"2022-01-13T09:44:25+00:00","author":{"@id":"https:\/\/zdmaa.com\/tr\/ro\/#\/schema\/person\/8aad4cf5d562d4ca835487f6149853e3"},"breadcrumb":{"@id":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/#breadcrumb"},"inLanguage":"tr","potentialAction":[{"@type":"ReadAction","target":["https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/"]}]},{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/#primaryimage","url":"https:\/\/zdmaa.com\/wp-content\/uploads\/2022\/01\/syringe-g03fb6e5bf_640.png","contentUrl":"https:\/\/zdmaa.com\/wp-content\/uploads\/2022\/01\/syringe-g03fb6e5bf_640.png","width":507,"height":640,"caption":"A simple blood test may help illustrate a patient's cancer"},{"@type":"BreadcrumbList","@id":"https:\/\/zdmaa.com\/tr\/a-simple-blood-test-may-help-illustrate-a-patients-cancer\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u0627\u0644\u0631\u0626\u064a\u0633\u064a\u0629","item":"https:\/\/zdmaa.com\/tr\/"},{"@type":"ListItem","position":2,"name":"Basit bir kan testi, bir hastan\u0131n kanserini netle\u015ftirmeye yard\u0131mc\u0131 olabilir"}]},{"@type":"WebSite","@id":"https:\/\/zdmaa.com\/tr\/ro\/#website","url":"https:\/\/zdmaa.com\/tr\/ro\/","name":"zdmaa","description":"zdmaa","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/zdmaa.com\/tr\/ro\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"tr"},{"@type":"Person","@id":"https:\/\/zdmaa.com\/tr\/ro\/#\/schema\/person\/8aad4cf5d562d4ca835487f6149853e3","name":"admin","image":{"@type":"ImageObject","inLanguage":"tr","@id":"https:\/\/zdmaa.com\/tr\/ro\/#\/schema\/person\/image\/","url":"https:\/\/zdmaa.com\/wp-content\/litespeed\/avatar\/dff6d89ac221c1aaf9366bf5b4cd32de.jpg?ver=1775954700","contentUrl":"https:\/\/zdmaa.com\/wp-content\/litespeed\/avatar\/dff6d89ac221c1aaf9366bf5b4cd32de.jpg?ver=1775954700","caption":"admin"},"sameAs":["https:\/\/zdmaa.com"],"url":"https:\/\/zdmaa.com\/tr\/author\/admin\/"}]}},"_links":{"self":[{"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/posts\/24505","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/comments?post=24505"}],"version-history":[{"count":2,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/posts\/24505\/revisions"}],"predecessor-version":[{"id":24565,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/posts\/24505\/revisions\/24565"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/media\/23242"}],"wp:attachment":[{"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/media?parent=24505"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/categories?post=24505"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zdmaa.com\/tr\/wp-json\/wp\/v2\/tags?post=24505"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}